合成6-6 雜環類緣物作為新穎組蛋白去乙醯酶抑制劑的研究

劉宜旻 - 臺北醫學大學藥學系(碩博士班) 學位論文, 2011 - airitilibrary.com
… the treatment of cutaneous T-cell lymphoma (CTCL) in 2006. Soon, FDA approved the second
HDACi, FK228 (Romidepsin, Istodax○R), also used in the treatment … , we discover that the …

I. 在脂鏈醯基羥胺嵌入芳香環吲哚開發新型組蛋白去乙醯酶抑制劑作為抗癌藥物II. 鄰位芳香環氮-羥基肉桂酸醯胺結構優化作為選擇性第八型組蛋白去乙醯酶抑制劑

王文揚 - 2014 - airitilibrary.com
Romidepsin both were FDA-approved HDAC inhibitors to treat Cutaneous T cell lymphoma
(… In this study, we used aryl indole as a surface recognition cap to develop a novel series of …

西达本胺联合阿扎胞苷治疗复发/难治性血管免疫母细胞性T 细胞淋巴瘤的前瞻性临床研究

魏冲, 赵丹青, 张炎, 王为, 张薇, 周道斌 - 中国癌症防治杂志, 2023 - zgazfz.com
… [摘要]目的探讨西达本胺联合阿扎胞苷治疗复发/难治性血管免疫母细胞性T细胞淋巴瘤(angioimmunoblastic
Tcell lymphoma,AITL)的疗效和安全性.方法本研究为单中心前瞻性临床研究,研究…

中耳间变性大T 细胞淋巴瘤1 例并文献复习

赵笑冰, 张大为, 陈仁杰 - 山东大学耳鼻喉眼学报, 2022 - ebhyxbwk.njournal.sdu.edu.cn
… large T-cell lymphoma is … history, systemic examination findings, pathological biopsy findings
and immunohistochemistry to diagnose middle ear anaplastic large T-cell lymphoma at an …

淋巴瘤表观遗传学靶向治疗的进展

苗昭艺, 赵智刚 - 中国肿瘤临床, 2020 - cjco.cn
… that the development and progression of lymphomas are … study of romidepsin in refractory
cutaneous T-cell lymphoma[J… study of romidepsin in relapsed or refractory peripheral Tcell

非特指EBV 阳性弥漫大B 细胞淋巴瘤的研究进展

陈光亮, 吴方恬, 曹军宁 - 中国癌症杂志, 2022 - china-oncology.com
… -Hodgkin’s lymphoma, NHL),结外自然杀伤/T细胞淋巴瘤(natural killer/T-cell lymphoma,NK/TL…
Histone deacetylase inhibitor romidepsin induces efficient tumor cell lysis via selective down…

[HTML][HTML] 赖氨酸乙酰化的研究进展及应用

杨雨薇, 尚爽, 胡卓伟, 花芳 - 药学学报, 2019 - html.rhhz.net
… Recently, the development of mass spectrometry has … Romidepsin (FK-228)是用于治疗
皮肤T细胞淋巴瘤(cutaneous T-cell lymphoma, CTCL)和外周T细胞淋巴瘤(peripheral T-cell

[HTML][HTML] 源于天然产物或其衍生物的分子靶向抗肿瘤药物研究进展

张旭, 蒙凌华 - 药学学报, 2020 - html.rhhz.net
… are essential for initiation and development of tumor, resulting … 罗米地辛(romidepsin)是一个
新的具有抗肿瘤活性的组蛋白去… T cell lymphoma, CTCL)和外周T细胞淋巴瘤(peripheral T cell

[HTML][HTML] 组蛋白去乙酰化酶抑制剂的抗抑郁前景

姚开云, 丁虹琬, 曹琳玉, 高银阁, 张建军, 王贵彬 - 药学学报, 2021 - html.rhhz.net
… 批准用于治疗难治性或复发性的皮肤T细胞淋巴瘤(cutaneous T-cell lymphoma, CTCL) [39]
. … (BDNF) and other neuronal growth factors involved in the development of depression.While …

MPT0E028 在人類大腸直腸癌與B 細胞淋巴癌之抗癌機轉探討

黃瀚立 - 2015 - tdr.lib.ntu.edu.tw
… and developed new drugs in Taiwan, the main goal of this thesis is to discover and develop
… US FDA approval for the treatment of patients with cutaneous T-cell lymphoma. In this study, …