… of miR-27 in liver contributes to hepatic lipogenesis. Here we test the hypothesis that miR-27
participates in insulin/Akt signaling, which is a critical regulator of liver metabolism. First, …

… liver are complex processes influenced by factors such as environment, diet, and genetics.
MicroRNAs (miRNAs), as post-transcriptional regulatory … in the regulation of liver development …

… of miR-27 in liver contributes to hepatic lipogenesis. Here we test the hypothesis that miR-27
participates in insulin/Akt signaling, which is a critical regulator of liver metabolism. First, …

… other to involve in the transcriptional regulations of the same genes. Up-regulation of CEBPD
can … stimuli, and is involved in the regulation of hepatic lipogenesis. In addition, CEBPD is …

… of the fatty acid synthesis transcription regulator SREBP1 (sterol regulatory element binding
protein 1) in the liver, and thus activated the transcription of the downstream fat synthesis …

… Furthermore, we identified another CEBPD regulated hepatic lipogenic gene-PPARG2
through the same bifunctional regulation. Base on our current study on COX-2 gene regulation, …

… non-selective agonist TO901317 induces hepatic lipogenesis and promotes the secretion of
… via the induction of lipogenic genes including sterol regulatory element binding protein 1c (…

… Interestingly, several studies demonstrated that CEBPD gene expression is down-regulated
and “loss of function” alterations in CEBPD gene expression were observed in human …

… involved in lipogenesis were also up-regulated in the liver of … as XBP1, a key transcriptional
regulator of unfolded protein … and transcription factor ATF4 were strongly activated in the liver …

… In order to test whether lipogenesis regulates AR transcriptional activity, we induced liver
lipogenesis pathway by replacement of normal chow into with high carbohydrate diet (HCD) in …