将蛋白质组学发现转化为治疗痴呆症药物的策略
A Halder, E Drummond - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… As more genomics, transcriptomics, and proteomics studies … of clinical efficacy is the major
reason for the failure of drugs … development to predict CNS penetration of drug compounds, …
reason for the failure of drugs … development to predict CNS penetration of drug compounds, …
[HTML][HTML] 结核病药物治疗的过去、 现状及未来
BI Kefan, CAO Dan, D Cheng, LU Shuihua… - … University (Medical …, 2022 - ncbi.nlm.nih.gov
… In the past 100 years, the discovery of revolutionary anti-TB drugs such as streptomycin, …
with drug combination treatment, has greatly improved TB control globally. As anti-TB drugs …
with drug combination treatment, has greatly improved TB control globally. As anti-TB drugs …
小胶质细胞的功能表型突出了慢性创伤性脑损伤和正常年龄相关病理学之间的黑暗关系
RM Ritzel, J Wu - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
… further investigation as our transcriptomic data revealed a large … Brain aging leads to a
decline in autophagy efficiency … state strongly imply epigenetic regulation. Both global protein …
decline in autophagy efficiency … state strongly imply epigenetic regulation. Both global protein …
视网膜对光感受器变性的神经和Müller 胶质细胞适应
HO Leinonen, E Bull, Z Fu - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
… However, the efficiency needs to be further improved in developed retinas. The long…
transcriptomics. The field could also be further advanced by the application of spatial transcriptomics …
transcriptomics. The field could also be further advanced by the application of spatial transcriptomics …
基于免疫微环境特征的曲妥珠单抗与免疫治疗联合应用预测模型
杨闻箫, 国琳玮, 凌泓, 胡欣 - 中国癌症杂志, 2023 - china-oncology.com
… to the efficacy of trastuzumab, indicating the clinical potential of … Methods: Transcriptome
and genome data of 509 HER2-… Regulation of immune effector process Negative regulation …
and genome data of 509 HER2-… Regulation of immune effector process Negative regulation …
微小RNA 作为诊断精神分裂症的潜在生物标志物及抗精神病药物治疗的影响
B Martinez, PV Peplow - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… predict the attenuated response of some therapeutic approaches to SZ (Kurtz, 2011).
Antipsychotic treatments have limited efficacy … This indicated that the combination of miR-181b-5p …
Antipsychotic treatments have limited efficacy … This indicated that the combination of miR-181b-5p …
[HTML][HTML] Crabp2 透過HuR 以及Integrin β1/FAK/ERK 訊息傳導促進肺癌細胞轉移
JI Wu - 2019 - ir.lib.ncu.edu.tw
… Regulatory circuits involved in the induction of connexins and their functional effects have
also been reported in various types of cancer. Here we focus on the recent findings in the …
also been reported in various types of cancer. Here we focus on the recent findings in the …
肠道微生物群与神经退行性疾病相关性分析: 一项基于宏基因组学的综述
X Liu, Y Liu, J Liu, H Zhang, C Shan, Y Guo… - 中国神经再生研究 …, 2024 - sjzsyj.com.cn
… important microbes or efficacious metabolites have been … for clinical use thanks to the success
of clinical metagenomic … C (2023b) Neuroimmune transcriptome changes in patient brains …
of clinical metagenomic … C (2023b) Neuroimmune transcriptome changes in patient brains …
2022 年度肝癌研究及诊疗新进展
赵海潮, 高强 - 中国癌症杂志, 2023 - china-oncology.com
… -research and clinical treatment and become the key to improving the treatment efficacy of …
an FDA pooled analysis of landmark clinical trials with validation from routine practice[J]. Eur J …
an FDA pooled analysis of landmark clinical trials with validation from routine practice[J]. Eur J …