[HTML][HTML] 天然产物生物合成与微生物制造的挑战*

李秋阳, 孙文涛, 秦磊, 吕波, 李春 - 中国生物工程杂志, 2024 - manu60.magtech.com.cn
… Engineering cellular metabolite transport for biosynthesis of computationally predicted
tropane alkaloid derivatives in yeast. Proceedings of the National Academy of Sciences of the …

[HTML][HTML] 茉莉酸甲酯处理对何首乌根转录组的影响

H Liu, W Wu, K Hou, J Chen, Z Zhao - Journal of Zhejiang University …, 2015 - Springer
… three alkaloid pathways were expressed under exogenous MeJA application. Eleven of 45
expressed genes participating in the “tropane, piperidine and pyridine alkaloid biosynthesis” …

中药药效成分群的合成生物学研究进展

查文龙, 卜兰, 訾佳辰 - 合成生物学, 2024 - synbioj.cip.com.cn
… groups, their key biosynthetic enzymes must be engineered … of key biosynthetic enzymes
(eg product ratio and catalytic … 9 Biosynthetic pathway of tropane alkaloids in A. belladonna …

[HTML][HTML] 药用植物生物碱次生代谢工程研究进展

黄玉香, 谭何新, 于剑, 张青磊, 郭志英, 陈越, 刁勇… - 中草药, 2016 - tiprpress.com
… Metabolic pathway of tropane alkaloids (dotted lines indicate a number of reaction steps) …
Engineering tropane biosynthetic pathway in Hyoscyamus niger hairy root cultures[J]. Proc Natl …

诱导子对药用植物毛状根活性次生代谢物生成的影响

周佳蕾, 方圆, 陈建伟 - Botanical Research, 2017 - hanspub.org
… improve the biosynthesis of phenolic acids, quinones, alkaloids, flavonoids, terpenoids,
triterpenoidsaponins in hairy roots of 16 medicinal plants. Conclusion: The production of …

[HTML][HTML] 罗汉果甜苷V 的合成生物学研究进展

孙泽敏, 吕波, 冯永君 - 生物工程学报, 2020 - cjb.ijournals.cn
pharmacological activity of mogroside V, and review progress in applying synthetic biology
for its synthesis… , to provide a reference for further studies on the biosynthesis of mogroside V. …

[HTML][HTML] 钩藤STR基因及其启动子的克隆与分析

周浩, 路星星, 敖雯雯, 廖海民, 张明生, 强玮 - 药学学报, 2022 - html.rhhz.net
: 根据钩藤转录组中STR 基因核心序列设计特异性引物, 并进行RACE 扩增, 克隆到UrSTR 基因(GeneBank:
OL310251) 的cDNA 全长1 541 bp, 编码345 个氨基酸; 采用染色体步移克隆到…

[HTML][HTML] 基于转录组测序的宁夏枸杞不同品种果实活性成分合成差异表达基因分析

刘雪霞, 范文强, 焦慧慧, 高寒, 唐建宁, 朱金忠… - 生物工程 …, 2023 - cjb.ijournals.cn
: 为探究不同品种宁夏枸杞果实活性成分生物合成相关基因的表达水平, 筛选关键差异表达基因(differentially
expressed genes, DEGs), 揭示宁夏枸杞品种间活性成分含量差异的分子机制, 本…

[HTML][HTML] 植物源二萜类化合物微生物合成研究进展

程亚田, 汤皓, 孙丽丽, 胡雅婷, 马莹, 郭娟, 黄璐琦 - 生物工程学报, 2023 - cjb.ijournals.cn
… CYP76AH1 catalyzes turnover of miltiradiene in tanshinones biosynthesis and enables
heterologous production of ferruginol in yeasts. Proceedings of the National Academy of …

[PDF][PDF] 服用苯巴比妥东莨菪碱自杀1 例

董塔娜, 张磊磊, 刘杰 - 法医学杂志, 2022 - fyxzz.cn
Tropane alkaloids: Chemistry, pharmacology, biosynthesis and production[J]. Molecules,2019,…
A review of toxic alkaloid poisoning and detection[J]. Zhongguo Weisheng Jianyan Zazhi,…