Monogenic diabetes: Implementation of translational genomic research towards precision medicine: 单基因糖尿病: 应用翻译基因组研究朝精准医疗迈进

M Vaxillaire, P Froguel - Journal of Diabetes, 2016 - Wiley Online Library
… are primarily characterized by functional defects of pancreatic β-… diabetes have led to the
identification of major genes and … approach is to carry out whole-exome sequencing (WES) in …

IS-S1-5 指_ H Repurposing of 4-phenylbutyrate for

H Hayashi - jstage.jst.go.jp
… Methods Consecutive patients with pancreatic cancer(PC) … of tumors in 12 cases with SVR-HCC
using whole-exome … This study aimed to clarify the incidences and characteristics of HM …

[PDF][PDF] 胰腺癌精准治疗的现状和展望

王欢, 金钢 - 中国普通外科杂志, 2021 - zpwz.net
… retain the molecular and biological characteristics of pancreatic cancer. Our center's practices
Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic …

[HTML][HTML] SWI/SNF 复合体基因突变促进NSCLC 细胞在NSI 小鼠体内肝转移的研究

GAO Lingling, XIE Zhi, LIN Shouheng… - … of Lung Cancer, 2023 - ncbi.nlm.nih.gov
… 我们使用全外显子组测序(whole-exome sequencing, WES)分析… WES analysis revealed
intracellular gene mutations. The … Transcriptome sequencing and Western blot analysis showed …

[HTML][HTML] 精准医疗与胰腺癌

朱世凯 - 世界华人消化杂志, 2016 - wjgnet.com
… The advent of big-data genomic era and the rapid development of … pancreatic cancer, with
an aim to provide new ideas for improving the survival rate of patients with pancreatic cancer

胰腺癌精准治疗: 从小众走向主流

罗国培, 虞先濬 - 中国癌症杂志, 2022 - china-oncology.com
… future for the precision treatment in pancreatic cancer. [Key words] … genomic characterization
of advanced pancreatic cancer to … Wholeexome sequencing of pancreatic neoplasms with …

[HTML][HTML] 从蛋白质基因组学视角出发的精准肿瘤学

黄雨柔, 吴松锋, 舒坤贤, 朱云平 - 生物工程学报, 2022 - cjb.ijournals.cn
… has certain limitations in molecular phenotype analysis, proteogenomics thus arose at the
… of proteomics and genomics. This review describes the limitations of genomic analysis and …

2020 年胰腺癌研究及诊疗新进展

唐榕, 施思, 张波, 徐近, 王巍, 虞先濬 - 中国癌症杂志, 2021 - china-oncology.com
… of pancreatic cancer eventually. The present review summarized the important findings in
pancreatic cancer … profiling: a retrospective analysis of the Know Your Tumor registry trial[J]. …

[PDF][PDF] 开发针对泛素特异性蛋白酶的高质量化学探针

童宇峰 - 中国药理学与毒理学杂志 - cjpt.magtechjournal.com
… Latest examples include the whole exome sequencing studies… 24] and the need of well-
characterized, high quality chemical … is a potent inhibitor of pancreatic cancer cell survival[J]. Mol …

肿瘤克隆进化与癌症发生研究进展

赵萱, 林东昕 - 中国癌症防治杂志, 2023 - zgazfz.com
: 恶性肿瘤发生是突变细胞克隆在内外源性因素作用下不断积累基因组变异与功能损伤的结果.
肿瘤克隆扩张的进程往往还伴随着更多组织器官无法自行修复的反应, 是一个多因素, 多阶段, …