Immunological detection of changes in genomic DNA methylation during early zebrafish development

AB MacKay, AA Mhanni, RA McGowan, PH Krone - Genome, 2007 - cdnsciencepub.com
… The demonstration of broad genomic DNA methylation changes during early zebrafish
development reported in this study further establishes a conserved pattern of DNA methylation in …

Variant Histone H2afv reprograms DNA methylation during early zebrafish development

B Madakashira, L Corbett, C Zhang, P Paoli… - Epigenetics, 2017 - Taylor & Francis
… between H2afv loss and DNA methylation, we analyzed total 5mC levels using genomic
DNA slot-blots probed with anti-5mC normalized to total genomic DNA (ds-DNA; Fig. 3A-B). Fig. …

Global and gene specific DNA methylation changes during zebrafish development

X Fang, J Corrales, C Thornton, BE Scheffler… - … and Physiology Part B …, 2013 - Elsevier
… we found that the timing of changes in DNA methylation patterns was gene specific, and
changes in gene expression were not necessarily correlated with the DNA methylation patterns. …

DNA methylation and gene expression alterations in zebrafish early-life stages exposed to the antibacterial agent triclosan

E Falisse, B Ducos, PA Stockwell, IM Morison… - Environmental …, 2018 - Elsevier
… of 171 differentially methylated fragments were identified by … between mRNA levels and DNA
methylation patterns in introns, … that Triclosan alters DNA methylation in zebrafish exposed …

[HTML][HTML] Enhancers reside in a unique epigenetic environment during early zebrafish development

LJT Kaaij, M Mokry, M Zhou… - Genome …, 2016 - genomebiology.biomedcentral.com
… , we find that DNA methylation status and enhancer activity during early zebrafish development
display very unusual correlation characteristics: hypo-methylation is a unique feature of …

Zebrafish as a model to study the role of DNA methylation in environmental toxicology

JH Kamstra, P Aleström, JM Kooter, J Legler - Environmental Science and …, 2015 - Springer
… In this review, recent insights in DNA methylation during zebra fish development are … study
the role of DNA methylation in environmental toxicology. Differences exist in DNA methylation

The specific alteration of histone methylation profiles by DZNep during early zebrafish development

O Østrup, AH Reiner, P Aleström, P Collas - Biochimica et Biophysica Acta …, 2014 - Elsevier
… We first investigated the effect of DZNep on early zebrafish development by growing
dechorionated 1–2 cell stage embryos in increasing DZNep concentrations for up to 120 h post-…

Role of epigenetics in zebrafish development

S Balasubramanian, A Raghunath, E Perumal - Gene, 2019 - Elsevier
… , the DNA methylation is required for genome imprinting, a significant process for viability
and MZT whereas the zebrafish doesn't have genome imprinting. The maternal genome of …

DNA methylation in zebrafish

MG Goll, ME Halpern - Progress in molecular biology and translational …, 2011 - Elsevier
… in a 30% reduction in genomic DNA methylation, as assayed by mass spectrometry and
HpaII digestion. In addition, the growth arrest and DNA damage protein Gad45, which had been …

Zebrafish embryos as a screen for DNA methylation modifications after compound exposure

MC Bouwmeester, S Ruiter, T Lommelaars… - Toxicology and applied …, 2016 - Elsevier
… In conclusion, the zebrafish embryo is a potential screening tool to examine DNA methylation
modifications after xenobiotic exposure. The next step is to examine the adult phenotype of …