… rate of GLUT4 exocytosis markedly increases concomitant with a small decrease in endocytosis
so that approximately 50% of the GLUT4 … The rate of exocytosis subsequently decreases …

… mimics the effect of insulin on GLUT4 translocation, we examined the effect of myr-Akt1 on
GLUT4's intracellular distribution. Myr-Akt1 decreased the fraction of GLUT4 in the specialized …

… Several recent reviews have covered other aspects of insulin-regulated glucose transport,
including insulin signalling, GLUT4 endocytosis and formation of GLUT4 vesicles. We will not …

… Although the entire process has been classically called GLUT4 translocation, we here break
it down into transport to the periphery and peripheral events. Most studies also agree that …

… GLUT4. To separately determine the exocytic and endocytic rates of GLUT4, we describe the
… for measuring the amount of cell surface GLUT4 at steady-state ( Basic Protocol 1), GLUT4 …

… Glut4 to the plasma membrane by increasing the rate of Glut4 exocytosis (through an increase
in the exocytic … Glut4 endocytosis from the plasma membrane (through a decrease in the …

… exocytosis while slowing GLUT4myc endocytosis. CaMKIIδ and AMPK stimulate GLUT4myc
exocytosis, whereas novel PKCs reduce endocytosis. … GLUT4 exocytosis and endocytosis in …

… Although GLUT4 exocytosis has been studied extensively, GLUT4 endocytosis and its
possible … Recent studies have begun to shed light on GLUT4 endocytic mechanisms and their …

… In summary, the most important signalling pathway to evoke Glut4 translocation is the Akt/PKB
pathway. The Cbl/TC10 pathway could also be involved in the tethering of …

… pathway of GLUT4 into exocytosis and endocytosis and … that both exocytosis and
endocytosis of GLUT4 are regulated … necessary for endocytosis of GLUT4 but not for exocytosis. …