[HTML][HTML] Identification of colorectal cancer related genes with mRMR and shortest path in protein-protein interaction network

BQ Li, T Huang, L Liu, YD Cai, KC Chou - PloS one, 2012 - journals.plos.org
… to identify the disease genes. In this study, we developed a computational method to identify
colorectal cancer-… analysis of functional protein association networks. The former has been …

Network cluster analysis of protein–protein interaction network identified biomarker for early onset colorectal cancer

T Luo, S Wu, X Shen, L Li - Molecular biology reports, 2013 - Springer
… In Asia, it is the fourth leading cause of cancer-related mortality, and the incidence is …
colorectal cancer (HNPCC) and familial adenomatous polyposis (FAP) have been identified by …

[HTML][HTML] Identification of key pathways and genes in colorectal cancer to predict the prognosis based on mRNA interaction network

H Zhu, Y Ji, W Li, M Wu - Oncology Letters, 2019 - spandidos-publications.com
… The aim of the present study was to identify key genes in colorectal cancer (CRC) that
could be used to reliably diagnose this disease and to explore the potential underlying …

[HTML][HTML] Identification and interaction analysis of molecular markers in colorectal cancer by integrated bioinformatics analysis

B Han, D Feng, X Yu, Y Zhang, Y Liu… - Medical science monitor …, 2018 - ncbi.nlm.nih.gov
… -protein interaction network, and demonstrated that 5 key genes are associated with the
overall survival of CRC patients. We also identified 8 DEMs that form a gene signal network with …

Hub genes and key pathway identification in colorectal cancer based on bioinformatic analysis

J Lv, L Li - BioMed Research International, 2019 - Wiley Online Library
… The hub genes are the highly connected nodes in the PPI network, which have high … in
various types of cancer. The Protein-Protein Interaction (PPI) network and hub genes analysis are …

[HTML][HTML] An integrative-omics approach to identify functional sub-networks in human colorectal cancer

RK Nibbe, M Koyutürk, MR Chance - PLoS computational biology, 2010 - journals.plos.org
… -network markers in human colorectal cancer, based on a seed of differentially expressed
proteins identified … Is the Subject Area "Protein interaction networks" applicable to this article? …

A network-based, integrative approach to identify genes with aberrant co-methylation in colorectal cancer

Y Li, J Xu, H Ju, Y Xiao, H Chen, J Lv, T Shao… - Molecular …, 2014 - pubs.rsc.org
interaction network (PPIN), affect several cancer-associated pathways and form hotspots that
are frequently hijacked in cancer… In this study, the protein–protein interaction network (PPIN…

[HTML][HTML] Revealing the molecular mechanism of colorectal cancer by establishing LGALS3‑related protein-protein interaction network and identifying signaling …

L Han, Z Wu, Q Zhao - International journal of …, 2014 - spandidos-publications.com
… In this study, the DEGs were identified between colorectal cancer and normal samples and
their functions were predicted by GO analysis. The pathways which these DEGs dysregulated …

An integrated approach to identify causal network modules of complex diseases with application to colorectal cancer

Z Wen, ZP Liu, Z Liu, Y Zhang… - Journal of the American …, 2013 - academic.oup.com
… –protein interaction network, we developed a novel algorithm to identify causal network
modules of … First, we define candidate causal genes as either known cancer genes or genes with …

Identification of key genes in colorectal cancer diagnosis by weighted gene co-expression network analysis

M Mortezapour, L Tapak, F Bahreini, R Najafi… - Computers in Biology …, 2023 - Elsevier
… Afterward, the Protein-protein interaction network through … were identified through the
evaluation of constructed network … Based on the results of the mRNA-miRNA interaction network, …