人脐带间充质干细胞来源外泌体靶向小胶质细胞减轻帕金森病神经细胞损伤

ZX Zhang, YJ Zhou, P Gu, W Zhao, HX Chen… - 中国神经再生研究 …, 2023 - sjzsyj.com.cn
… hucMSC-Exos improve PD by inhibiting microglia-mediated pyroptosis. … pyroptosis in vitro.
Moreover, we carried out a preliminary investigation of the possible underlying mechanism

[HTML][HTML] A549 细胞氧糖剥夺/恢复模型中焦亡与凋亡的共享信号通路

安雨轩, 肖宗懿, 王小燕, 宋娟, 陈菲, 王寿勇 - 2022 - aammt.tmmu.edu.cn
… Shared signaling pathway in pyroptosis and apoptosis in A549 cells induced by oxygen
and glucose deprivation/recovery[J]. Journal of Army Medical University, 2022, 44(11): 1119-…

[HTML][HTML] 附子理中丸治疗肠结核作用机制的网络药理学研究

苏敏, 钱纯, 张贞, 姜思宇, 李菁, 李云豪, 周辉 - 世界华人消化杂志, 2023 - wjgnet.com
targets, and 2579 disease targets were screened from the public database. A total of 134
potential therapeutic targets and 10 core targets (… that the biological mechanism of Fuzi Lizhong …

线粒体功能障碍在脓毒性心肌病中的研究进展

张共鹏, 程志鹏, 魏艳龙, 尚志文, 董孝彧… - 蚌埠医学院 …, 2022 - xuebao.bbmc.edu.cn
Potential therapy strategy: targeting mitochondrial dysfunction in sepsis[J]. Mil Med Res, …
Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes …

中枢神经系统的血管炎症

X Guo, Z Zhao - 中国神经再生研究(英文版), 2022 - sjzsyj.com.cn
… , oxidative stress, pyroptosis and breakdown of epithelial barrier. … Vascular inflammation as
a potential CNS therapeutic target: … an attractive CNS therapeutic target for the treatment of a …

[PDF][PDF] 潜质未定克隆性造血致动脉粥样硬化及NLRP3 炎性小体治疗作用研究进展

陈雅芳, 李思, 史洋, 魏丽萍 - 中国医药导报 - yiyaodaobao.com.cn
… inhibitory effect on NLRP3 inflammasome mediated pyroptosis. Therefore, MCC950 is … by
the regulation of pyroptosis by NLRP3 inflammasome, and the role and mechanism of selective …

嘌呤能抑制剂在免疫介导疾病中的临床应用之路崎岖

MT Wyss, C Heuer, M Herwerth - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… We have recently identified a new mode of action that could partly explain the anti-… as a
possible therapeutic target for inflammatory diseases. In comparison, the field of possible use of …

[HTML][HTML] 负载焦亡抑制剂的活性氧响应性自组装纳米胶束对糖尿病大鼠全层皮肤缺损的影响

欧泽林, 王珏, 时荣, 邓君, 刘毅… - 中华烧伤与创面修复 …, 2023 - zhsszz.xml-journal.net
… nanomicelle loaded with pyroptosis inhibitor on full-thickness skin defects in diabetic rats. …
The DEG heatmap of the NOD-like receptor pathway, a pyroptosis-related pathway, was made. …

Pin1 在神经元死亡中的调控作用

SC Wang, XM Hu, K Xiong - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
… the development of therapeutic target for neurodegenerative … the critical regulatory mechanisms
associated with Pin1 in … by tumor necrosis factor, pyroptosis that relies on the activation …

绝经后骨质疏松症潜在铁死亡及细胞焦亡相关诊断生物标志物

李树栋, 梁学振, 骆帝, 李嘉程, 阎博昭, 李刚 - 中国组织工程研究, 2024 - cjter.com
… so as to further elucidate their biological mechanisms. … with ferroptosis and pyroptosis
for the potential diagnosis of … a promising therapeutic target. Front Immunol. 2022;13:972753. …