Role of the NFκB-signaling pathway in cancer

L Xia, S Tan, Y Zhou, J Lin, H Wang… - OncoTargets and …, 2018 - Taylor & Francis
… , and VEGF, NFκB mediates tumor-cell proliferation, survival, and angiogenesis. Citation9
This … focuses on this NFκB-signaling pathway in tumors. Overview of NFκB-signaling pathways

A beginner's guide to NFκB signaling pathways

S Delhalle, R Blasius, M Dicato… - Annals of the New York …, 2004 - Wiley Online Library
… Several steps of the NF-κB signal transduction pathway, such as IKK activation, IκB
phosphorylation and degradation, NF-κB nuclear translocation, and transcriptional activity, can be …

[HTML][HTML] Non-canonical NF-κB signaling pathway

SC Sun - Cell research, 2011 - nature.com
The non-canonical NF-κB pathway is an important arm of NF-κB signaling that predominantly
targets activation of the p52/RelB NF-κB complex. This pathway depends on the inducible …

SnapShot: NF-κB signaling pathways

MS Hayden, AP West, S Ghosh - Cell, 2006 - cell.com
… PKC phosphorylates CARMA1 resulting in activation and oligomerization of the CBM
complex, recruitment of TRAF6, and stimulation of the classical TAK1 to IKK signaling pathway. …

[PDF][PDF] NF-κB signaling pathway and free radical impact

A Siomek - Acta Biochimica Polonica, 2012 - bibliotekanauki.pl
… redox events regulate the NF-κB pathway is still unclear. … NF-κB signaling pathway.
Phosphorylation and dephosphorylation processes are crucial in the activation of preexisting NF-κB

[HTML][HTML] NF-κB signaling pathways in osteoarthritic cartilage destruction

MC Choi, J Jo, J Park, HK Kang, Y Park - Cells, 2019 - mdpi.com
… In this review, we discuss the roles of NF-κB in OA chondrocytes and related signaling
pathways, … potential therapeutic targets that can interfere with NF-κB signaling for OA treatment. …

[HTML][HTML] NFκB-dependent signaling pathways

X Li, GR Stark - Experimental hematology, 2002 - Elsevier
… Once activated, TAK1 can directly phosphorylate IKKβ and MKK6, leading to the activation
of both the JNK and NFκB signaling pathways. TAK1 is also activated upon stimulation by …

NFκB signaling

E O'Dea, A Hoffmann - Wiley Interdisciplinary Reviews …, 2009 - Wiley Online Library
… A group of noninflammatory signals have been shown to activate NF-κB through the (noncanonical)
NF-κB signaling pathway. These developmental signals of the TNF-receptor …

Molecular basis of NF-κB signaling

J Napetschnig, H Wu - Annual review of biophysics, 2013 - annualreviews.org
… proteins is tightly regulated, and inappropriate activation of the NF-κB signaling pathways has
… in the NF-κB signaling pathway is the regulation of the interaction between NF-κB and the …

Signaling to NF-κB

MS Hayden, S Ghosh - Genes & development, 2004 - genesdev.cshlp.org
pathway with the complexity of responses in which NF-κB family members play important
roles. In this review, we provide an overview of established NF-κB signaling pathwaysNF-κB