Perineuronal nets: subtle structures with large implications

H Carceller, Y Gramuntell, P Klimczak… - The …, 2023 - journals.sagepub.com
Perineuronal nets (PNNs) are specialized structures of the extracellular matrix that surround
the soma and proximal dendrites of certain neurons in the central nervous system, …

Casting a wide net: role of perineuronal nets in neural plasticity

BA Sorg, S Berretta, JM Blacktop… - Journal of …, 2016 - Soc Neuroscience
Perineuronal nets (PNNs) are unique extracellular matrix structures that wrap around
certain neurons in the CNS during development and control plasticity in the adult CNS. They …

Impact of perineuronal nets on electrophysiology of parvalbumin interneurons, principal neurons, and brain oscillations: a review

JC Wingert, BA Sorg - Frontiers in synaptic neuroscience, 2021 - frontiersin.org
Perineuronal nets (PNNs) play such a critical role in PV interneuron function that recent cell-…
Finally, to bring together the broader implications of PNN removal on PV interneuron function…

The roles of perineuronal nets and the perinodal extracellular matrix in neuronal function

JW Fawcett, T Oohashi, T Pizzorusso - Nature Reviews Neuroscience, 2019 - nature.com
… b | The structure of the perinodal ECM is similar to that of perineuronal nets (PNNs), with
chondroitin sulfate proteoglycans (CSPGs) — particularly brevican, neurocan and versican — …

Perineuronal nets: plasticity, protection, and therapeutic potential

AC Reichelt, DJ Hare, TJ Bussey, LM Saksida - Trends in neurosciences, 2019 - cell.com
… The ECM has emerged as an important participant in synaptic plasticity, and in particular
the structures comprised of condensed ECM known as perineuronal nets (PNNs); [ …

Distribution of N‐Acetylgalactosamine‐Positive Perineuronal Nets in the Macaque Brain: Anatomy and Implications

AL Mueller, A Davis, S Sovich, SS Carlson… - Neural …, 2016 - Wiley Online Library
… the important role of perineuronal nets in plasticity in the visual … the distribution of perineuronal
nets in representative areas of … The incidence of perineuronal nets around parvalbumin-…

The perineuronal net and the control of CNS plasticity

D Wang, J Fawcett - Cell and tissue research, 2012 - Springer
Perineuronal nets (PNNs) are reticular structures that surround the cell body of many
neurones, and extend along their dendrites. They are considered to be a specialized extracellular …

From molecules to behavior: Implications for perineuronal net remodeling in learning and memory

B Sanchez, P Kraszewski, S Lee… - Journal of …, 2023 - Wiley Online Library
… FIGURE 1 Overview of the structure and composition of perineuronal nets (PNNs). Many
different extracellular matrix components organize together to form the mesh- like structure of …

Perineuronal Nets as Therapeutic Targets for the Treatment of Neuropsychiatric Disorders

CA Browne, K Conant, AW Lasek… - Frontiers in Synaptic …, 2022 - frontiersin.org
Perineuronal nets (PNNs) are condensed portions of the extracellular matrix (ECM) that
stabilize homeostatic synaptic plasticity, facilitate neuronal-glia communication, and provide a …

Perineuronal nets in brain physiology and disease

D Testa, A Prochiantz, AA Di Nardo - Seminars in cell & developmental …, 2019 - Elsevier
… We also describe its role in various brain functions and its ensuing implication in several
brain disorders. Finally, we survey approaches to change PNN expression, which include not …