Abstract Interleukin (IL)-1 gene family encodes for pleiotropic pro-inflammatory and anti-
inflammatory cytokines. Genome screens mapped asthma phenotypes to chromosome 2q12 …

Abstract Background and Aim Interleukin‐1 is a pro‐inflammatory cytokine found in two
forms (α and β). The α form is mainly cell‐bound, whereas IL‐1β is primarily secreted by …

Abstract Background Interleukin 4 (IL4) is a key cytokine that regulates the inflammatory
cascade in bronchial asthma. We investigated the association between the IL4 and IL4R …

Abstract Background: Interleukins (IL) 4 and 13 genes and their receptors (R) are the key
cytokines which amplify inflammatory reactions in asthma. Objective: This study aimed to …

Objective To evaluae possible association between interleukin-1 beta (IL-1?) gene exon 5
polymorphism and childhood asthma. Methods The study was conducted in two different …

Abstract Background: Interleukins (IL) 4 and 13 genes and their receptors (R) are the key
cytokines which amplify inflammatory reactions in asthma. Objective: This study aimed to …

Asthma is a complex genetic disease. Genetic and functional characteristics of interleukin
(IL)-1 support a role as an asthma locus for the IL-1 family on chromosome 2q12–21. This …

Objective To investigate the association of two single-nucleotide polymorphisms (SNPs) in
IL1R1 gene (rs1558641 and rs949963) with the susceptibility to asthma in children from …

The present study aims to investigate the association between the genetic polymorphisms of
interferon (IFN)-γ and interleukin (IL)-4 with childhood susceptibility to asthma and the levels …

Asthma is a chronic inflammatory disease of the airway. Both genetic and environmental
factors are thought to be involved in the onset of the disease. We aimed to investigate if the …