Skeletal muscle has an extraordinary capacity to regenerate after injury and trauma. The
muscle repair mechanism is a complex process orchestrated by multiple steps. In …

Skeletal muscle has an extraordinary capacity to regenerate after injury and trauma. The
muscle repair mechanism is a complex process orchestrated by multiple steps. In …

Utrophin is an autosomal ubiquitously expressed protein, with structural homology to
dystrophin. It is found at the muscle sarcolemma in utero and is progressively replaced by …

Utrophin is an autosomal paralogue of dystrophin, a protein whose deficit causes Duchenne
and Becker muscular dystrophies (DMD/BMD). Utrophin is naturally overexpressed at the …

Utrophin is an autosomal ubiquitously expressed protein, with structural homology to
dystrophin. It is found at the muscle sarcolemma in utero and is progressively replaced by …

Duchenne muscular dystrophy is a fatal childhood disease caused by mutations that abolish
the expression of dystrophin in muscle. Utrophin is a paralogue of dystrophin and can …

This month in Med, the description of an unusually severely affected DMD patient suffering
from a large deletion in the dystrophin gene confirms that absence of utrophin worsens the …

Duchenne muscular dystrophy is a severe and currently incurable progressive
neuromuscular condition, caused by mutations in the DMD gene that result in the inability to …

The continual expression of utrophin protein by pharmacological maintenance of utrophin
transcription in dystrophin deficient muscle fibres is a potential disease modifying treatment …

Utrophin is an autosomal ubiquitously expressed protein, with structural homology to
dystrophin. It is found at the muscle sarcolemma in utero and is progressively replaced by …