Characterization of differentially methylated regions in 3 bovine imprinted genes: a model for studying human germ-cell and embryo development
T Hansmann, J Heinzmann, C Wrenzycki… - … and Genome Research, 2011 - karger.com
Correct imprinting is crucial for normal fetal and placental development in mammals.
Experimental evidence in animal models and epidemiological studies in humans suggest …
Experimental evidence in animal models and epidemiological studies in humans suggest …
[HTML][HTML] DNA methylation in the IGF2 intragenic DMR is re-established in a sex-specific manner in bovine blastocysts after somatic cloning
C Gebert, C Wrenzycki, D Herrmann, D Gröger, J Thiel… - Genomics, 2009 - Elsevier
The recent identification of an intragenic differentially methylated region (DMR) within the
last exon of the bovine Insulin-like growth factor 2 (IGF2) gene provides a diagnostic tool for …
last exon of the bovine Insulin-like growth factor 2 (IGF2) gene provides a diagnostic tool for …
Characterization of the methylation status of five imprinted genes in sheep gametes
A Colosimo, G Di Rocco, V Curini, V Russo… - Animal …, 2009 - Wiley Online Library
Genomic imprinting is a mammalian developmental process that uses epigenetic
mechanisms to induce monoallelic and parental‐specific expression of particular autosomal …
mechanisms to induce monoallelic and parental‐specific expression of particular autosomal …
Methylation status of putative differentially methylated regions of porcine IGF2 and H19
This study was designed to identify the putative differentially methylated regions (DMRs) of
the porcine imprinted genes insulin‐like growth factor 2 and H19 (IGF2‐H19), and to assess …
the porcine imprinted genes insulin‐like growth factor 2 and H19 (IGF2‐H19), and to assess …
Methylation dynamics of imprinted genes in mouse germ cells
D Lucifero, C Mertineit, HJ Clarke, TH Bestor… - Genomics, 2002 - Elsevier
DNA methylation differences between maternal and paternal alleles of many imprinted
genes are inherited from the male and female gametes and subsequently maintained during …
genes are inherited from the male and female gametes and subsequently maintained during …
mRNA Levels of Imprinted Genes in Bovine In Vivo Oocytes, Embryos and Cross Species Comparisons with Humans, Mice and Pigs
Z Jiang, H Dong, X Zheng, SL Marjani, DM Donovan… - Scientific Reports, 2015 - nature.com
Twenty-six imprinted genes were quantified in bovine in vivo produced oocytes and
embryos using RNA-seq. Eighteen were detectable and their transcriptional patterns were …
embryos using RNA-seq. Eighteen were detectable and their transcriptional patterns were …
DNA methylation changes during preimplantation development reveal inter-species differences and reprogramming events at imprinted genes
Preimplantation embryos experience profound resetting of epigenetic information inherited
from the gametes. Genome-wide analysis at single-base resolution has shown similarities …
from the gametes. Genome-wide analysis at single-base resolution has shown similarities …
[HTML][HTML] The bovine IGF2 gene is differentially methylated in oocyte and sperm DNA
C Gebert, C Wrenzycki, D Herrmann, D Gröger… - Genomics, 2006 - Elsevier
The insulin-like growth factor 2 gene (IGF2) encodes an essential growth factor and is
imprinted in various mammalian species. Differentially methylated regions (DMRs) are often …
imprinted in various mammalian species. Differentially methylated regions (DMRs) are often …
Epigenetic profile of developmentally important genes in bovine oocytes
J Heinzmann, T Hansmann, D Herrmann… - Molecular …, 2011 - Wiley Online Library
Assisted reproductive technologies are associated with an increased incidence of
epigenetic aberrations, specifically in imprinted genes. Here, we used the bovine oocyte as …
epigenetic aberrations, specifically in imprinted genes. Here, we used the bovine oocyte as …
Is ART changing the epigenetic landscape of imprinting?
W Mak, JR Weaver… - Animal Reproduction …, 2018 - animal-reproduction.org
Imprinted genes, which are epigenetically modified such that only a single parental allele is
expressed, are often regulated by imprinting control regions (ICRs). ICRs typically are DNA …
expressed, are often regulated by imprinting control regions (ICRs). ICRs typically are DNA …