Treatment of high-risk patients with ezetimibe plus simvastatin co-administration versus simvastatin alone to attain National Cholesterol Education Program Adult …

T Feldman, M Koren, W Insull Jr, J McKenney… - The American journal of …, 2004 - Elsevier
This study assessed whether the co-administration of ezetimibe and simvastatin would be
more effective than simvastatin monotherapy in allowing high-risk patients to achieve a low …

Efficacy and safety of ezetimibe co-administered with simvastatin compared with atorvastatin in adults with hypercholesterolemia

CM Ballantyne, MA Blazing, TR King, WE Brady… - The American journal of …, 2004 - Elsevier
This study compared the efficacy and safety of co-administered ezetimibe+ simvastatin with
atorvastatin monotherapy in adults with hypercholesterolemia. Seven hundred eighty-eight …

Ezetimibe coadministered with simvastatin in patients with primary hypercholesterolemia

MH Davidson, T McGarry, R Bettis, L Melani… - Journal of the American …, 2002 - jacc.org
Objectives: The purpose of this study was to assess the efficacy and safety of ezetimibe
administered with simvastatin in patients with primary hypercholesterolemia. Background …

Efficacy and safety of ezetimibe added to ongoing statin therapy for treatment of patients with primary hypercholesterolemia

C Gagné, HE Bays, SR Weiss, P Mata, K Quinto… - The American journal of …, 2002 - Elsevier
Ezetimibe is a lipid-lowering drug that inhibits the intestinal absorption of dietary and biliary
cholesterol by blocking passage across the intestinal wall. The efficacy and safety of adding …

Achieving lipoprotein goals in patients at high risk with severe hypercholesterolemia: efficacy and safety of ezetimibe co-administered with atorvastatin

E Stein, S Stender, P Mata, P Sager, D Ponsonnet… - American heart …, 2004 - Elsevier
BACKGROUND: Despite the efficacy of statins in lowering low-density lipoprotein
cholesterol (LDL-C) levels, many patients who are at high risk for heart disease with …

Efficacy and safety of ezetimibe coadministered with simvastatin in patients with primary hypercholesterolemia: a randomized, double-blind, placebo-controlled trial

AC Goldberg, A Sapre, J Liu, R Capece… - Mayo Clinic …, 2004 - Elsevier
Objective To compare the efficacy and safety of 10 mg of ezetimibe coadministered with
simvastatin with the safety and efficacy of simvastatin monotherapy for patients with …

Effectiveness of ezetimibe alone or in combination with twice a week Atorvastatin (10 mg) for statin intolerant high-risk patients

VG Athyros, K Tziomalos, AI Kakafika… - The American journal of …, 2008 - Elsevier
This study was undertaken to investigate the effect of ezetimibe (10 mg/day) alone or in
combination with atorvastatin (10 mg twice a week) on hypercholesterolemia in 56 high-risk …

Effect of co-administering ezetimibe with on-going simvastatin treatment on LDL-C goal attainment in hypercholesterolemic patients with coronary heart disease

M Farnier, M Volpe, R Massaad, MJ Davies… - International journal of …, 2005 - Elsevier
OBJECTIVE: To determine whether co-administering ezetimibe with on-going simvastatin
treatment was more effective than placebo plus on-going simvastatin in achieving an LDL-C …

Efficacy and safety of ezetimibe added to atorvastatin versus atorvastatin uptitration or switching to rosuvastatin in patients with primary hypercholesterolemia

HE Bays, M Averna, C Majul, D Muller-Wieland… - The American journal of …, 2013 - Elsevier
Hypercholesterolemic patients (n= 1,547) at high atherosclerotic cardiovascular disease risk
with low-density lipoprotein cholesterol (LDL-C) levels≥ 100 and≤ 160 mg/dl while treated …

Safety and efficacy of ezetimibe added on to rosuvastatin 5 or 10 mg versus up-titration of rosuvastatin in patients with hypercholesterolemia (the ACTE Study)

HE Bays, MH Davidson, R Massaad, D Flaim… - The American journal of …, 2011 - Elsevier
The present multicenter, 6-week, randomized, double-blind, parallel-group, clinical trial
evaluated the safety and efficacy of ezetimibe (10 mg) added to stable rosuvastatin therapy …