TET 酶的生物学功能及相关机制的研究进展
曾雨冰， 何学佳， 刘帆， 裴培， 王珊 - 生物技术进展, 2022 - swjsjz.cn
DNA 甲基化(DNA methylation) 及去甲基化属于常见的表观遗传修饰, 可介导多种生理和病理
过程. DNA 甲基化及去甲基化修饰参与基因的表达调控, 且二者的动态平衡可以维持遗传表达 …
过程. DNA 甲基化及去甲基化修饰参与基因的表达调控, 且二者的动态平衡可以维持遗传表达 …
TET 蛋白: 一个新的DNA 修饰酶家族
郭晓强， 王越甲， 郭振清， 常彦忠， 段相林 - 中国生物化学与分子生物学报, 2011 - cqvip.com
DNA 的胞嘧啶(C) 5-甲基化是一种重要的表观修饰, 它参与基因调节, 基因组印记, X-
染色体失活, 重复序列抑制和癌症发生等过程. 5-甲基胞嘧啶(5mC) 可被TET (ten-eleven …
染色体失活, 重复序列抑制和癌症发生等过程. 5-甲基胞嘧啶(5mC) 可被TET (ten-eleven …
Acetylation regulates TET2 stability and enzymatic activity
DNA methylation, one of the key epigenetic modifications in the mammalian genome, plays
fundamental roles in development and disease. Although DNA methylation and DNA …
fundamental roles in development and disease. Although DNA methylation and DNA …
Mechanisms of TET protein-mediated DNA demethylation and its role in the regulation of mouse development.
J Zhenwei, G Shuxin, Z Yongchun, Z Xianhua - Yi chuan= Hereditas, 2015 - europepmc.org
TET (ten-eleven translocation) protein family includes three members TET1, TET2 and TET3,
which belong to alpha-ketoglutaric acid (α-KG)-and Fe (2+)-dependent dioxygenase …
which belong to alpha-ketoglutaric acid (α-KG)-and Fe (2+)-dependent dioxygenase …
Role of TET enzymes in DNA methylation, development, and cancer
KD Rasmussen, K Helin - Genes & development, 2016 - genesdev.cshlp.org
The pattern of DNA methylation at cytosine bases in the genome is tightly linked to gene
expression, and DNA methylation abnormalities are often observed in diseases. The ten …
expression, and DNA methylation abnormalities are often observed in diseases. The ten …
Tet 基因家族与DNA 去甲基化
程瑶， 刘小珊 - 汕头大学医学院学报, 2013 - cqvip.com
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Research advances in TET enzyme and its intermediate product 5hmC
J Wu, X Fang, X Xia, M Zhang - Zhong nan da xue xue bao. Yi xue …, 2019 - europepmc.org
DNA methylation is a significant epigenetic modification mode, which plays an important role
in embryo reprogramming, stem cell differentiation and tumor occurrence. The ten-eleven …
in embryo reprogramming, stem cell differentiation and tumor occurrence. The ten-eleven …
Advances in the DNA methylation hydroxylase TET1
W Liu, G Wu, F Xiong, Y Chen - Biomarker research, 2021 - Springer
Background The ten-eleven translocation 1 (TET1) protein is a 5-methylcytosine
hydroxylase that belongs to the TET protein family of human α-ketoglutarate oxygenases …
hydroxylase that belongs to the TET protein family of human α-ketoglutarate oxygenases …
Structure and function of TET enzymes
X Yin, L Hu, Y Xu - DNA Methyltransferases-Role and Function, 2022 - Springer
Mammalian DNA methylation mainly occurs at the carbon-C5 position of cytosine (5mC).
TET enzymes were discovered to successively oxidize 5mC to 5-hydromethylcytosine …
TET enzymes were discovered to successively oxidize 5mC to 5-hydromethylcytosine …
[HTML][HTML] TET 蛋白家族与5-羟甲基胞嘧啶在干细胞及再生医学表观遗传调控中的作用
赵健芳， 李东， 安阳 - Journal of Peking University (Health Sciences …, 2021 - ncbi.nlm.nih.gov
The methylation of cytosine is one of the most fundamental epigenetic modifications in
mammalian genomes, and is involved in multiple crucial processes including gene …
mammalian genomes, and is involved in multiple crucial processes including gene …