Vaccine-based immunotherapy for head and neck cancers

S Beyaert, JP Machiels, S Schmitz - Cancers, 2021 - mdpi.com
Simple Summary Therapeutic vaccines are given to patients with cancer, as opposed to
prophylactic vaccines given to a healthy population. The challenge for therapeutic …

Therapeutic human papillomavirus vaccines in head and neck cancer: a systematic review of current clinical trials

K Schneider, C Grønhøj, CH Hahn, C von Buchwald - Vaccine, 2018 - Elsevier
Objectives This systematic review provides an overview of the current clinical trials
investigating therapeutic vaccines for HPV+ head and neck cancer and discusses the future …

Therapeutic Vaccination in Head and Neck Squamous Cell Carcinoma—A Review

K Devaraja, S Aggarwal, M Singh - Vaccines, 2023 - mdpi.com
Therapeutic vaccination is one of the most effective immunotherapeutic approaches, second
only to immune checkpoint inhibitors (ICIs), which have already been approved for clinical …

Human papillomavirus therapeutic vaccines in head and neck tumors

G Badaracco, A Venuti - Expert Review of Anticancer Therapy, 2007 - Taylor & Francis
Head and neck cancer represents one of the most challenging diseases as the mortality
remains high despite advances in early diagnosis and treatment. Human papillomavirus has …

[HTML][HTML] Tolerability and efficacy of the cancer vaccine UV1 in patients with recurrent or metastatic PD-L1 positive head and neck squamous cell carcinoma planned for …

A Brandt, C Schultheiss, K Klinghammer… - Frontiers in …, 2024 - frontiersin.org
Background Globally, head and neck squamous cell carcinoma (HNSCC) is the seventh
most common malignancy. Despite aggressive multimodal treatment approaches, recurrent …

Therapeutic vaccination for HPV-mediated cancers

F Yan, LG Cowell, A Tomkies, AT Day - Current Otorhinolaryngology …, 2023 - Springer
Abstract Purpose of Review The goal of this narrative review is to educate clinicians
regarding the foundational concepts, efficacy, and future directions of therapeutic vaccines …

HPV vaccination in head and neck HPV-related pathologies

M Wierzbicka, A Józefiak, J Jackowska… - Otolaryngologia …, 2014 - Elsevier
Recent data demonstrate that human papilloma virus (HPV) plays a role in pathologies other
than ano-genital cancers, specifically head and neck malignancies, and non-cancerous …

Targeting immune response with therapeutic vaccines in premalignant lesions and cervical cancer: hope or reality from clinical studies

P Vici, L Pizzuti, L Mariani, G Zampa… - Expert review of …, 2016 - Taylor & Francis
Human papillomavirus (HPV) is widely known as a cause of cervical cancer (CC) and
cervical intraepithelial neoplasia (CIN). HPVs related to cancer express two main …

Anti-tumor vaccines in head and neck cancer: targeting immune responses to the tumor

TL Whiteside - Current Cancer Drug Targets, 2007 - ingentaconnect.com
Immune therapies aiming at the destruction of a residual tumor and inducing tumor-specific
memory responses are gaining acceptance among clinicians treating head and neck …

Therapeutic vaccines for HPV-associated oropharyngeal and cervical cancer: the next de-intensification strategy?

GB Morand, I Cardona, SBSC Cruz… - International Journal of …, 2022 - mdpi.com
The rise in human papillomavirus (HPV)-associated oropharyngeal squamous cell
carcinoma (OPSCC) has prompted a quest for further understanding of the role of high-risk …