Current Status and Future Perspective in Glioma Invasion Research

T Ohnishi - Brain Sciences, 2024 - mdpi.com
Glioblastoma (GBM) is the most malignant brain tumor in adults and shows an extremely
poor prognosis, with a median survival of 15 months [1]. The main reason for this poor …

Molecular mechanisms and clinical challenges of glioma invasion

T Oishi, S Koizumi, K Kurozumi - Brain Sciences, 2022 - mdpi.com
Glioma is the most common primary brain tumor, and its prognosis is poor. Glioma cells are
highly invasive to the brain parenchyma. It is difficult to achieve complete resection due to …

Mechanisms regulating glioma invasion

I Paw, RC Carpenter, K Watabe, W Debinski, HW Lo - Cancer letters, 2015 - Elsevier
Glioblastoma (GBM) is the most aggressive, deadliest, and most common brain malignancy
in adults. Despite the advances made in surgical techniques, radiotherapy and …

Tumor cell invasion in glioblastoma

A Vollmann-Zwerenz, V Leidgens, G Feliciello… - International journal of …, 2020 - mdpi.com
Glioblastoma (GBM) is a particularly devastating tumor with a median survival of about 16
months. Recent research has revealed novel insights into the outstanding heterogeneity of …

Therapeutic strategies for inhibiting invasion in glioblastoma

J Drappatz, AD Norden, PY Wen - Expert review of …, 2009 - Taylor & Francis
Glioblastomas are the most common and lethal form of malignant primary brain tumors.
Although some progress has been made, the impact of recent advances in multimodality …

Tumor Cell Invasion and the Tumor Microenvironment: Special Focus on Brain Tumors

T Daubon, R Magaut, A Bikfalvi - Tumor Microenvironment: Novel …, 2021 - Springer
Tumor cell invasion is a major issue in oncology since it leads to tumor dissemination and
recurrence. In glioblastomas, invasion is an important characteristic, making the disease …

Intrinsic and Microenvironmental Drivers of Glioblastoma Invasion

E De Fazio, M Pittarello, A Gans, B Ghosh… - International journal of …, 2024 - mdpi.com
Gliomas are diffusely infiltrating brain tumors whose prognosis is strongly influenced by their
extent of invasion into the surrounding brain tissue. While lower-grade gliomas present more …

Tumor cell infiltration into the brain in glioblastoma: from mechanisms to clinical perspectives

F Seker-Polat, N Pinarbasi Degirmenci, I Solaroglu… - Cancers, 2022 - mdpi.com
Simple Summary The estimated survival time for glioblastoma patients is extremely low; only
about 5% of patients survive five years post diagnosis. The standard of care for glioblastoma …

Molecular targets of glioma invasion

M Nakada, S Nakada, T Demuth, NL Tran… - Cellular and molecular …, 2007 - Springer
Glioblastoma multiforme is the most common and lethal primary malignant brain tumor.
Although considerable progress has been made in technical proficiencies of surgical and …

[HTML][HTML] Glioblastoma multiforme: Diagnosis, treatment, and invasion

J Li, L Feng, Y Lu - Journal of Biomedical Research, 2023 - ncbi.nlm.nih.gov
Glioblastoma multiforme (GBM) is an essentially incurable brain tumor, which has been
explored for approximately a century. Nowadays, surgical resection, chemotherapy, and …