Glucose–insulin homeostasis, lipid profiles and GH-IGF-IGFBP axis in clozapine-treated schizophrenic obesity versus non-psychiatric obesity

MK Wu, CY Huang, YJ Liou, CK Wang… - International Journal of …, 2008 - nature.com
Objective: Obese patients with schizophrenia being treated with clozapine and non-
psychiatric obese are often assumed to share the same physiological changes in obesity …

[HTML][HTML] Outcomes of obese, clozapine-treated inpatients with schizophrenia placed on a six-month diet and physical activity program

MK Wu, CK Wang, YM Bai, CY Huang… - Psychiatric …, 2007 - Am Psychiatric Assoc
Objective: Patients with schizophrenia treated with clozapine often gain weight. This study
evaluated the effects of dietary control and physical activity among obese inpatients with …

Different influences of classical antipsychotics and clozapine on glucose-insulin homeostasis in patients with schizophrenia or related psychoses

KI Melkersson, AL Hulting, KE Brismar - Journal of Clinical …, 1999 - psychiatrist.com
Background: The aim of this study was to investigate the influence of classical antipsychotics
and the atypical antipsychotic agent clozapine on glucoseinsulin homeostasis to explain …

Blood levels of glucose and insulin and insulin resistance in patients with schizophrenia on clozapine monotherapy

A Wysokiński - Diabetes & Metabolic Syndrome: Clinical Research & …, 2014 - Elsevier
Objective We tested the hypothesis that fasting blood glucose and insulin levels are higher
in schizophrenic subjects on clozapine monotherapy compared with healthy controls and …

High prevalence of prediabetes and metabolic abnormalities in overweight or obese schizophrenia patients treated with clozapine or olanzapine

JR Larsen, CK Svensson, L Vedtofte, ML Jakobsen… - CNS …, 2019 - cambridge.org
ObjectiveTo assess the prevalence of prediabetes and metabolic abnormalities among
overweight or obese clozapine-or olanzapine-treated schizophrenia patients, and to identify …

[HTML][HTML] Changes in body fat and related biochemical parameters associated with atypical antipsychotic drug treatment in schizophrenia patients with or without …

EG Kornetova, AN Kornetov, IA Mednova… - Frontiers in …, 2019 - frontiersin.org
Background: Metabolic syndrome (MetS) is a common problem in schizophrenia patients
and associated with increased mortality due to cardiovascular disease. Second-generation …

Prevalence of obesity and clinical and metabolic correlates in first-episode schizophrenia relative to healthy controls

Y Tian, D Wang, G Wei, J Wang, H Zhou, H Xu… - …, 2021 - Springer
Objective People with schizophrenia exhibit a high obesity rate. However, little is known
about the prevalence of obesity and its relationship with clinical symptoms and metabolic …

Changes in neuroendocrine and metabolic hormones induced by atypical antipsychotics in normal-weight patients with schizophrenia

V Popovic, M Doknic, N Maric, S Pekic… - …, 2007 - karger.com
Context: Atypical antipsychotics (SGA) have the propensity to induce weight gain. Objective:
The aim was to evaluateearly changes in hormones involved in neuroendocrine regulations …

Low prevalence of obesity and metabolic syndrome in never-treated chronic schizophrenia

R Padmavati, RG McCreadie, S Tirupati - Schizophrenia research, 2010 - Elsevier
INTRODUCTION: Antipsychotic medication and lifestyle factors are implicated in the high
rates of obesity and metabolic syndrome in schizophrenia. While the two Consensus …

[HTML][HTML] Does schizophrenia itself cause obesity?

J Liang, Y Cai, X Xue, X Li, Z Li, C Xu, G Xie… - Frontiers in …, 2022 - frontiersin.org
Background Schizophrenia (SC) is considered the most serious of all mental disorders.
Some antipsychotics are associated with weight gain and metabolic abnormalities. Whether …