PD-L1 expression correlation with metabolic parameters of FDG PET/CT and clinicopathological characteristics in non-small cell lung cancer

X Wu, Y Huang, Q Zhao, L Wang, X Song, Y Li… - EJNMMI research, 2020 - Springer
Background Immunotherapy targeting programmed cell death 1 (PD-1) or its ligand 1 (PD-
L1) has shown promising results in non-small cell lung cancer (NSCLC) patients. Exploring …

18F-FDG PET metabolic-to-morphological volume ratio predicts PD-L1 tumour expression and response to PD-1 blockade in non-small-cell lung cancer

M Jreige, I Letovanec, K Chaba, S Renaud… - European journal of …, 2019 - Springer
Abstract Purpose Anti-PD-1/PD-L1 blockade can restore tumour-specific T-cell immunity and
is an emerging therapy in non-small-cell lung cancer (NSCLC). We investigated the …

Association between PD-L1 expression and metabolic activity on 18F-FDG PET/CT in patients with small-sized lung cancer

K Takada, G Toyokawa, T Tagawa, K Kohashi… - Anticancer …, 2017 - ar.iiarjournals.org
Aim: We evaluated the metabolic characteristics of small-sized lung cancer using 18F-
fluorodeoxyglucose positron-emission tomography/computed tomography (18F-FDG …

PD-L1 in Lung Adenocarcinoma: Insights into the Role of 18F-FDG PET/CT

Y Cui, X Li, B Du, Y Diao, Y Li - Cancer Management and Research, 2020 - Taylor & Francis
Purpose This study aimed to evaluate the role of 18F-fluorodeoxyglucose (18F-FDG)
positron emission tomography (PET)/computed tomography (CT) in expression of tumor …

Evaluation of PD-L1 Expression Level in Patients With Non-Small Cell Lung Cancer by 18F-FDG PET/CT Radiomics and Clinicopathological Characteristics

J Li, S Ge, S Sang, C Hu, S Deng - Frontiers in Oncology, 2021 - frontiersin.org
Purpose In the present study, we aimed to evaluate the expression of programmed death-
ligand 1 (PD-L1) in patients with non-small cell lung cancer (NSCLC) by radiomic features of …

Metabolic characteristics of programmed cell death‐ligand 1‐expressing lung cancer on 18F‐fluorodeoxyglucose positron emission tomography/computed …

K Takada, G Toyokawa, T Okamoto, S Baba… - Cancer …, 2017 - Wiley Online Library
Abstract Programmed cell death‐1 (PD‐1) and programmed cell death‐ligand 1 (PD‐L1)
have been identified as novel targets of immunotherapy of lung cancer. In present study, we …

Predicting PD-L1 expression status in patients with non-small cell lung cancer using [18F]FDG PET/CT radiomics

X Zhao, Y Zhao, J Zhang, Z Zhang, L Liu, X Zhao - EJNMMI research, 2023 - Springer
Background In recent years, immune checkpoint inhibitor (ICI) therapy has greatly changed
the treatment prospects of patients with non-small cell lung cancer (NSCLC). Among the …

18F-FDG maximum standard uptake value predicts PD-L1 expression on tumor cells or tumor-infiltrating immune cells in non-small cell lung cancer

B Hu, W Chen, Y Zhang, H Shi, D Cheng… - Annals of Nuclear Medicine, 2020 - Springer
Objectives Programmed cell death-ligand 1 (PD-L1) is expressed on tumor cells (TC) and
tumor-infiltrating immune cells (IC). We conducted a retrospective study to investigate the …

Metabolic activity by 18F–FDG-PET/CT is predictive of early response after nivolumab in previously treated NSCLC

K Kaira, T Higuchi, I Naruse, Y Arisaka, A Tokue… - European journal of …, 2018 - Springer
Background Nivolumab, an anti-programmed death-1 (PD-1) antibody, is administered in
patients with previously treated non-small cell lung cancer. However, little is known about …

Prognostic Potential of Metabolic Activity on 18F-FDG Accumulation in Advanced NSCLC Receiving Combining Chemotherapy Plus PD-1 Blockade

K Hashimoto, K Kaira, H Imai, A Mouri… - Journal of …, 2022 - journals.lww.com
Combined chemotherapy plus programmed death-1 (PD-1) blockade is an established
treatment against patients with advanced non–small cell lung cancer (NSCLC). However, a …