The testis-enriched genes ZNF230/Znf230 are located on human chromosome
11p15/mouse chromosome 7 near conserved imprinting control regions. Typical CpG …

Tissue-specific gene expression is regulated by epigenetic modification involving trans-
acting factors. Here, we identified that the human MAGEB16 gene and its mouse homolog …

Mice with maternal duplication of proximal chromosome 6 die in utero at an early embryonic
stage. Recently, two imprinted genes, paternally expressed Sgce and maternally expressed …

In contrast to most genes in mammalian genomes, imprinted genes are monoallelically
expressed depending on the parental origin of the alleles. Imprinted gene expression is …

Imprinted genes are characterized by monoallelic expression that is dependent on parental
origin. Comparative analysis of imprinted genes between species is a powerful tool for …

Peg3 (p aternally e xpressed g ene 3) is the first imprinted gene detected in the proximal
region of mouse chromosome 7. Because imprinting is a trait that is generally conserved …

Genomic imprinting arises from allele-specific epigenetic modifications that are established
during gametogenesis and that are maintained throughout somatic development. These …

Parent-of-origin–dependent expression of imprinted genes is mostly associated with allele-
specific DNA methylation of the CpG islands (CGIs) called germ line differentially methylated …

Genomic imprinting is a conserved epigenetic phenomenon in eutherian mammals, with
regards both to the genes that are imprinted and the mechanism underlying the expression …

Background Differential DNA methylation plays a critical role in the regulation of imprinted
genes. The differentially methylated state of the imprinting control region is inherited via the …