The present invention was aimed to develop pharmaceutically equivalent, stable, cost
effective and quality improved formulation of cilnidipine with enhanced dissolution rate and …

Solid dispersion technique has been developed many years for improving solubility of water-
insoluble drugs, aiming to achieve a better oral bioavailability. However, this technique …

Improved bioavailability is an added advantage for most of the poorly water soluble drugs. In
recent years research work is concentrated on various methods to improve the solubility …

The aim of this study is to formulate and evaluate cilnidipine nanocrystals (CLD NCs) using
solvent antisolvent technology. Cilnidipine has a very low solubility (BCS Class-II drug low …

Materials and Methods: Cilostazol agglomerates were prepared using various polymers with
varying concentration of hydroxypropyl methylcellulose E 50 (HPMC E50), polyvinyl …

Background Cilnidipine, a calcium channel blocker, is the first-line drug for hypertension and
belongs to Biopharmaceutics Classification System II. To mitigate its extensive first-pass …

The objective of the present work was to improve micromeritic properties and dissolution
rate of a poorly water soluble drug, carvedilol, by spherical agglomeration in presence of …

Aim: Cilnidipine is a new antihypertensive agent and it is categorized under the
biopharmaceutical Class-II drug. Hence, our perspective is to improve dissolution through in …

The main objective of the work was to improve the dissolution rate of the drug, Cilnidipine
(CLD) by using the liquisolid compact technique and wet granulation. Cilnidipine drug is …

The objective of the present study is to improve the solubility of Biopharmaceutical
Classification System (BCS) Class-II drug, Cilnidipine by formulating them as solid …