诱导多能干细胞衍生的脑细胞, 类器官, 组装体和血脑屏障模型在理解酒精和麻醉剂诱导的脑损伤中的应用: 一个新的视角
X Bai - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
Neurological disorders, including developmental disorders, Alzheimer's disease (AD), and
psychiatric conditions, have significant social and economic impacts globally. Despite …
psychiatric conditions, have significant social and economic impacts globally. Despite …
[HTML][HTML] Use of induced pluripotent stem cell-derived brain cells, organoids, assembloids, and blood-brain barrier models in understanding alcohol and anesthetic …
X Bai - Neural Regeneration Research, 2024 - journals.lww.com
Neurological disorders, including developmental disorders, Alzheimer's disease (AD), and
psychiatric conditions, have significant social and economic impacts globally. Despite …
psychiatric conditions, have significant social and economic impacts globally. Despite …
Modeling alcohol-induced neurotoxicity using human induced pluripotent stem cell-derived three-dimensional cerebral organoids
T Arzua, Y Yan, C Jiang, S Logan, RL Allison… - Translational …, 2020 - nature.com
Maternal alcohol exposure during pregnancy can substantially impact the development of
the fetus, causing a range of symptoms, known as fetal alcohol spectrum disorders (FASDs) …
the fetus, causing a range of symptoms, known as fetal alcohol spectrum disorders (FASDs) …
Using human stem cells as a model system to understand the neural mechanisms of alcohol use disorders: current status and outlook
MS Scarnati, A Halikere, ZP Pang - Alcohol, 2019 - Elsevier
Alcohol use disorders (AUDs), which include alcohol abuse and dependence, are among
the most common types of neuropsychiatric disorders in the United States (US) …
the most common types of neuropsychiatric disorders in the United States (US) …
Postmortem-derived iPSC models in substance use disorders research
EF Mendez, C Walss-Bass - Neuropsychopharmacology, 2024 - nature.com
Patient-derived induced pluripotent stem cell (iPSC) models have accelerated discovery in
the biomedical sciences, with high potential to model human physiology and disease. The …
the biomedical sciences, with high potential to model human physiology and disease. The …
High-content analysis for ethanol-induced mitochondrial and neuronal toxicity in human iPSC-derived neurons
A Zink - 2021 - refubium.fu-berlin.de
Ethanol is the most frequently abused drug in the world with a worldwide mortality of three
million deaths each year (5.3% in 2016). Excessive ethanol consumption can adversely …
million deaths each year (5.3% in 2016). Excessive ethanol consumption can adversely …
Utilizing human induced pluripotent stem cells in the study of alcohol use disorder
R Lieberman - 2016 - digitalcommons.lib.uconn.edu
Alcohol use disorder is a complex, heterogeneous disorder that affects≈ 14% of the US
population. Much of what is known about the molecular effects of alcohol on the brain has …
population. Much of what is known about the molecular effects of alcohol on the brain has …
Recent advances in 3D-cultured brain tissue models derived from human iPSCs
Neurological diseases are caused by defects in the brain, spinal cord, or nervous system.
Excluding animal models, ex vivo brain tissues and brain organoids have been used for …
Excluding animal models, ex vivo brain tissues and brain organoids have been used for …
Alcohol-responsive genes identified in human iPSC-derived neural cultures
Alcohol use contributes to numerous diseases and injuries. The nervous system is affected
by alcohol in diverse ways, though the molecular mechanisms of these effects are not clearly …
by alcohol in diverse ways, though the molecular mechanisms of these effects are not clearly …
[HTML][HTML] Studying human neurological disorders using induced pluripotent stem cells: from 2D monolayer to 3D organoid and blood brain barrier models
S Logan, T Arzua, SG Canfield… - Comprehensive …, 2019 - ncbi.nlm.nih.gov
Neurological disorders have emerged as a predominant healthcare concern in recent years
due to their severe consequences on quality of life and prevalence throughout the world …
due to their severe consequences on quality of life and prevalence throughout the world …