Alzheimer's disease is a neurodegenerative disease that accounts for most of the 50-million
dementia cases worldwide in 2018. A large amount of evidence supports the amyloid …

Alzheimer's disease is a neurodegenerative disease that accounts for most of the 50-million
dementia cases worldwide in 2018. A large amount of evidence supports the amyloid …

阿尔茨海默病(Alzheimer's Disease, AD) 是一种以进行性认知功能减退包括记忆障碍和痴呆为
特征的神经变性疾病, 主要的病理特征包括: 神经细胞外以β-淀粉样蛋白(β-amyloid protein, Aβ) …

Alzheimer's disease (AD) is characterized by β-amyloid (Aβ) plaques consisted primarily of
aggregated Aβ proteins and neurofibrillary tangles formed by hyperphosphorylated tau …

阿尔茨海默病(AD) 神经病理学特征为中枢神经纹状体和新皮质产生大量神经炎性斑块(NPs)
和神经纤维缠结(NFTs), 痴呆是由于大脑患病处神经元及突触死亡所致, NPs …

Alzheimer's disease is characterized by the extracellular accumulation of the amyloid β in
the form of amyloid plaques and the intracellular deposition of the microtubule-associated …

Alzheimer's disease (AD) is the most common neurodegenerative disorder and is
characterized pathologically by the progressive intracellular accumulation of neurofibrillary …

Based on the amyloid hypothesis, studies on for Alzheimer disease (AD) therapy mostly
focus on elimination of beta-amyloid. However, results of recent studies on amyloid …

Objective: To review recent research advances on tau, a major player in Alzheimer's disease
(AD) pathogenesis, a biomarker for AD onset, and potential target for AD therapy. Data …

The aggregation of amyloid-beta peptide and tau protein dysregulation are implicated to
play key roles in Alzheimer's disease pathogenesis and are considered the main …