The perihematomal edema (PHE) after intracerebral hemorrhage (ICH) is one of the
manifestations of secondary brain injury. It is generally believed that the formation of PHE is …

Purpose The aim of this study was to investigate the temporal evolution of perihematomal
blood-brain barrier (BBB) compromise and edema growth and to determine the role of BBB …

Purpose Blood–brain barrier (BBB) damage aggravates perihematomal edema, and edema
volume predicts prognosis independently. But the BBB permeability at the late stage of acute …

Perihematomal edema (PHE) has been represented as an important secondary injury after
intracerebral hemorrhage (ICH). The evolution of PHE contributed to mass effect, which …

This paper summarized the main research progress which was relevant to the potential
mechanisms of secondary blood-brain barrier (BBB) dysfunction in adults' intracerebral …

Background and Purpose—Knowledge about cytotoxic edema (CE) in intracerebral
hemorrhage is still limited. We aimed to analyze its presence, temporal pattern, and …

Intracerebral hemorrhage (ICH) has one of the worst prognoses among patients with stroke.
Surgical measures have been adopted to relieve the mass effect of the hematoma, and …

The prognosis of patients with spontaneous intracerebral hemorrhage (sICH) is poor. It is of
great significance to improve the neurological function of these patients and make them …

The classification and mechanism of perihematomal edema in cerebral hemorrhage are
complicated. The edema theory in different periods needs to be unified due to various …

Dynamic contrast-enhanced (DCE) MRI is proposed as a tool to detect blood-brain barrier
(BBB) injury in patients with acute intracerebral hemorrhage (ICH). In this study, DCE MRI …