抄録< jats: title> Summary</jats: title>< jats: p> Terminology. Replace the term “Hemorrhagic
Disease of the Newborn”(HDN) by “Vitamin K Deficiency Bleeding”(VKDB), as neonatal …

Terminology. Replace the term “Hemorrhagic Disease of the Newborn”(HDN) by “Vitamin K
Deficiency Bleeding”(VKDB), as neonatal bleeding is often not due to VK-deficiency and …

The historical term “hemorrhagic disease of the newborn,” which is used as a synonym for
vitamin K deficiency bleeding (VKDB) in infancy, preferably should be abandoned, since …

Vitamin K-deficiency bleeding (VKDB) is rare, unpredictable, and life-threatening. Warning
signs such as minimal bleeds, evidence of cholestasis, and failure to thrive often are present …

Vitamin K is essential for the synthesis of few coagulation factors. Infants can easily develop
vitamin K deficiency owing to poor placental transfer, low vitamin K content in breast milk …

At the start of the 20th century the mechanisms of haemostasis were virtually unknown.
Townsend had coined the term 'Haemorrhagic disease of the newborn'in 1894 but it was not …

Fat-soluble vitamin K is a critical part of the activation of coagulation factors II (prothrombin),
VII, IX, and X. Compared with adults and older children, newborns have much lower levels of …

Intramuscular administration of vitamin K for prevention of vitamin K deficiency bleeding
(VKDB) has been a standard of care since the American Academy of Pediatrics …

Oral or parenteral administration of vitamin K is the accepted practice for prevention of early
vitamin K deficiency bleeding (VKDB) in the newborn. However, vitamin K prophylaxis in the …

There is consensus that late vitamin K deficiency bleeding (VKDB) should be prevented by
vitamin K prophylaxis. One single dose of 1 mg vitamin K 1 is effective if given im or sc, but …