青光眼基因治疗的概念——尚未实现的梦想

R Sulak, X Liu, A Smedowski - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
Gene therapies, despite of being a relatively new therapeutic approach, have a potential to
become an important alternative to current treatment strategies in glaucoma. Since …

[HTML][HTML] The concept of gene therapy for glaucoma: the dream that has not come true yet

R Sulak, X Liu, A Smedowski - Neural regeneration research, 2024 - journals.lww.com
Gene therapies, despite of being a relatively new therapeutic approach, have a potential to
become an important alternative to current treatment strategies in glaucoma. Since …

Gene therapy of glaucoma: Just an attractive experimental approach?

N Comes - Acta Ophthalmologica, 2022 - Wiley Online Library
In recent years, much progress has been made in the identification of the genes involved in
the physiology of glaucoma and the development of new gene‐based therapies. The …

Gene therapy strategies for glaucomatous neurodegeneration

R Lani-Louzada, MS Dias, R Linden… - Current Gene …, 2021 - ingentaconnect.com
Glaucoma leads to irreversible vision loss and current therapeutic strategies are often
insufficient to prevent the progression of the disease and consequent blindness. Elevated …

[HTML][HTML] Monogenic gene therapy for glaucoma and optic nerve injury

C Harada, X Guo, T Harada - Neural Regeneration Research, 2025 - journals.lww.com
The prevalence of glaucoma, the second leading cause of global blindness, is increasing
due to aging populations. In glaucoma, degeneration of the optic nerve and retinal ganglion …

[HTML][HTML] Perspective on Gene Therapy for Glaucoma

MS Dias, VG de Araujo, R Lani-Louzada… - … Recent Advances and …, 2022 - intechopen.com
Glaucoma is a chronic and multifactorial neurodegenerative disease marked by structural
damage to the optic nerve with axonal loss, progressive retinal ganglion cell degeneration …

Gene therapy for glaucoma

AM Demetriades - Current opinion in ophthalmology, 2011 - journals.lww.com
Gene therapy for glaucoma : Current Opinion in Ophthalmology Gene therapy for glaucoma :
Current Opinion in Ophthalmology Log in or Register Subscribe to journalSubscribe Get new …

Gene therapy strategies for glaucoma from IOP reduction to retinal neuroprotection: progress towards non-viral systems

A Hakim, B Guido, L Narsineni, DW Chen… - Advanced drug delivery …, 2023 - Elsevier
Glaucoma is the result of the gradual death of retinal ganglion cells (RGCs) whose axons
form the optic nerve. Elevated intraocular pressure (IOP) is a major risk factors …

[HTML][HTML] Adeno-associated virus mediated gene therapy for neuroprotection of retinal ganglion cells in glaucoma

C Starr, B Chen - Vision Research, 2023 - Elsevier
Glaucoma is a group of diseases typically characterized by the degeneration of the optic
nerve and is one of the world's leading causes of blindness. Although there is no cure for …

Gene Therapy for Neurodegeneration in Glaucoma

JJ Karl, HC Tseng - Advances in Vision Research, Volume IV: From Basic …, 2024 - Springer
Glaucoma is a leading cause of irreversible visual impairment and blindness worldwide.
Although it has been well established that neurodegeneration plays a key role in the …