中草藥對LPS 活化NF-kB 抑制機轉之研究

吳昱珊, 袁俊傑 - 2003 - ir.lib.nycu.edu.tw
轉錄因子NF-kB 在免疫發炎反應, 細胞的增生, 分化與癌化等生理反應中扮演了關鍵性的角色,
且也與許多疾病的發生有相關性. NF-kB 平時會與其調控蛋白IkB 結合, 而形成一個不活化的 …

[引用][C] 轉錄因子NF-kB 調控基因之表現機制及藥物探索(2/3)

陳青周 - 2004 - ntur.lib.ntu.edu.tw
The signaling pathway involved in TNF--induced cyclooxygenase-2 (COX-2) expression
was further studied in human NCI-H292 epithelial cells. A protein kinase C (PKC) inhibitor …

Nfkb1 Inhibits LPS-Induced IFN-β and IL-12 p40 Production in Macrophages by Distinct Mechanisms

X Zhao, EJ Ross, Y Wang, BH Horwitz - PLoS One, 2012 - journals.plos.org
Background Nfkb1-deficient murine macrophages express higher levels of IFN-β and IL-12
p40 following LPS stimulation than control macrophages, but the molecular basis for this …

痘病毒蛋白CP77 抑制NF-kB 訊息傳遞之機制

張書蓉 - 2008 - airitilibrary.com
Tumor necrosis factor a (TNF-a) stimulates inflammation via activation of the nuclear factor-
kB (NF-kB) transcriptional regulator. The NF-kB transcription factor family regulates …

Expression of HIF-1 inducible genes in the aged rat liver

JH Lee, MJ Kang, TH Park, KJ Jung… - Proceedings of the …, 2001 - koreascience.kr
The transCription factOf NFKB is a key Iegulator of the Cellular inflammatory and immune
fesponse. Therefore, Components Of the NFKB-activating Signaling pathways are frequent …

A novel non-Rel subunit of NF-kB confers its regulatory specificity (136.2)

F Wan, MJ Lenardo - The Journal of Immunology, 2009 - journals.aai.org
NF-kB regulates many important immunity, inflammation and anti-apoptosis genes. It still
remains largely unknown how NF-kB activates selected gene expression. We hypothesized …

Ming Li, David F. Carpio, Ye Zheng, Peter Bruzzo, Veena Singh

F Ouaaz, RM Mezhitov, AA Beg - NF-KB-dependent Host Defense … - search.proquest.com
Tissue damage induced by infection or injury can result in necrosis, a mode of cell death
characterized by induction of an inflammatory response. In contrast, cells dying by apoptosis …

[PDF][PDF] Monitoring NF-kB Transactivation Potential Via Real-Time PCR. Quantification of IkB-O Gene Expression

V Bottero, V Imbert, C Frelin, JL Formento, JF Peyron - researchgate.net
Conclusion: The real-time PCR measure of IkB-ot mRNA levels is a rapid, sensitive, and
powerful method to quantify the transcriptional power of NF-kB. It can be easily used for …

P-glycoprotein is not functionally overexpressed, and bcr/abl and bax is down regulated in cisplatin resistant human chronic myelogenous leukemia K562 cells

SY Lee, DH Kim - Proceedings of the PSK Conference, 2001 - koreascience.kr
The transCription factOf NFKB is a key Iegulator of the Cellular inflammatory and immune
fesponse. Therefore, Components Of the NFKB-activating Signaling pathways are frequent …

Inhibition of NF-kB 1 (NF-kBp50) by RNA interference in chicken macrophage HD11 cell line challenged with Salmonella enteritidis

HI Chiang, LR Berghman, H Zhou - Genetics and molecular biology, 2009 - SciELO Brasil
The NF-kB pathway plays an important role in regulating the immunity response in animals.
In this study, small interfering RNAs (siRNA) were used to specifically inhibit NF-kB 1 …