Regulation of hepatic differentiation of human embryonic stem cells by calcium silicate extracts for liver injury repairing

L Zheng, D Lü, F Zhang, M Xing, X Wang, X Jia… - Applied Materials …, 2020 - Elsevier
Directing embryonic stem cell (ESC)-derived hepatocytes is critical in understanding hepatic
differentiation and applying cell-based treatment to severe liver diseases. While growth …

Bioactive calcium silicate extracts regulate the morphology and stemness of human embryonic stem cells at the initial stage

F Zhang, D Lü, H Li, C Luo, J Chang, M Long - RSC advances, 2016 - pubs.rsc.org
Embryonic stem cells (ESCs) are undifferentiated cells that have the capacity to self-renew
and differentiate into a variety of cells and provide cell sources for regenerative medicine or …

Spheroid formation and differentiation into hepatocyte-like cells of rat mesenchymal stem cell induced by co-culture with liver cells

Z Qihao, C Xigu, C Guanghui, Z Weiwei - DNA and cell biology, 2007 - liebertpub.com
Mesenchymal stem cells (MSCs) derived from bone marrow have been shown to
differentiate into hepatocytes, which would be an ideal resource for transplantation or …

[引用][C] 硅酸钙浸出液与基底-细胞粘附调控人胚胎干细胞分化

郑璐 - 2021

多因子联合诱导人胚胎干细胞定向分化为肝细胞样细胞

崔罗方, 商昌珍, 任萌, 曹君, 吕丽虹, 陈亚进, 闵军 - 中华实验外科杂志, 2012 - cqvip.com
目的建立有效的体外诱导人胚胎干细胞(hESCs) 分化为肝细胞样细胞的培养体系.
方法将H9hESC 细胞株接种到基底膜提取物包被的培养板上, 序贯加入含有下列诱导因子的 …

含淤胆血清的培养体系体外诱导胚胎干细胞表达肝细胞功能的研究

方天翎, 闵军, 邓小耿, 钱世鹍, 褚忠华, 陈亚进, 邵静… - 中华肝脏病杂志, 2004 - cqvip.com
目的探讨病理微环境体外诱导对小鼠胚胎干细胞(ESC) 表达肝细胞功能的作用.
方法悬滴培养ESC 发育5~ 7d 的拟胚体, 将其离散细胞种植于不同的分化体系, 观察ESC …

Comparison of in vitro hepatogenic differentiation potential between various placenta-derived stem cells and other adult stem cells as an alternative source of …

HJ Lee, J Jung, KJ Cho, CK Lee, SG Hwang, GJ Kim - Differentiation, 2012 - Elsevier
Mesenchymal stem cells (MSCs) are powerful sources for cell therapy in regenerative
medicine. The capability to obtain effective stem cell-derived hepatocytes would improve cell …

Study of embryonic stem cells induced to express hepatic cell functions in vitro in a pathologic niche containing cholestatic serum

TL Fang, J Min, XG Deng, SK Qian, ZH Chu… - Zhonghua gan Zang …, 2004 - europepmc.org
Objective To study the role of a pathologic niche inducing mouse embryonic stem cells
(ESC) to express hepatic cell functions in vitro. Methods Embryoid bodies were developed …

胚胎干细胞/诱导多能干细胞向肝细胞诱导分化的研究进展

邢谦哲, 杜智 - 医学综述, 2016 - cqvip.com
人胚胎干细胞(ESCs)/诱导多能干细胞(i PSCs) 诱导生成的肝细胞为研究肝细胞分化分子机制,
肝病细胞模型的建立提供了很好的研究平台, 且诱导生成的肝细胞为新药开发 …

Selective enrichment of hepatocytes from mouse embryonic stem cells with a culture system containing cholestatic serum1

J Min, C SHANG, Y CHEN, L Zhang… - Acta …, 2007 - Wiley Online Library
Aim: There is increasing evidence indicating that embryonic stem (ES) cells are capable of
differentiating into hepatocyte‐like cells in vitro. However, it is necessary to improve the …