Analyzing DNA methylation patterns in Schizophrenic patients using machine learning methods

B Torabi Moghadam, M Etemadikhah, G Rajkova… - 2017 - diva-portal.org
Schizophrenia is common mental disorder with known genetic component involved. Since
the association of environmental factors and schizophrenia has been reported, we analyzed …

Analyzing DNA methylation patterns in subjects diagnosed with schizophrenia using machine learning methods

BT Moghadam, M Etemadikhah, G Rajkowska… - Journal of psychiatric …, 2019 - Elsevier
Schizophrenia is a common mental disorder with high heritability. It is genetically complex
and to date more than a hundred risk loci have been identified. Association of environmental …

Investigating DNA Methylation Changes Associated With Schizophrenia Using a Family-Based Approach

M Gaine, T Nickl-Jockschat… - Biological …, 2020 - biologicalpsychiatryjournal.com
Background Numerous genetic and environmental factors increase the complexity of
schizophrenia. These factors have the potential to cause systemic pathophysiological …

[HTML][HTML] Epigenetic profiling of human brain differential DNA methylation networks in schizophrenia

SA Lee, KC Huang - BMC medical genomics, 2016 - Springer
Background Epigenetics of schizophrenia provides important information on how the
environmental factors affect the genetic architecture of the disease. DNA methylation plays a …

Differential DNA methylation and network analysis in schizophrenia

HK Chuan - Computational epigenetics and diseases, 2019 - Elsevier
Schizophrenia is a multidimensional disorder, where a network analysis may be necessary
to create a better understanding on its etiology. Methods for DNA methylation of …

Genome-wide methylation profiling of schizophrenia

B Rukova, R Staneva, S Hadjidekova… - Balkan Journal of …, 2014 - sciendo.com
Schizophrenia is one of the major psychiatric disorders. It is a disorder of complex
inheritance, involving both heritable and environmental factors. DNA methylation is an …

Functional analysis of evolutionary human methylated regions in schizophrenia patients

N Banerjee, T Polushina, AK Stavrum, VM Steen… - bioRxiv, 2019 - biorxiv.org
Background Recent studies have implicated variations in DNA methylation in the aetiology
of schizophrenia. Genome-wide scans in both brain and blood report differential methylated …

A novel schizophrenia diagnostic model based on statistically significant changes in gene methylation in specific brain regions

D Zou, Y Qiu, R Li, Y Meng, Y Wu - BioMed Research …, 2020 - Wiley Online Library
Objective. The present study identified methylation patterns of schizophrenia‐(SCZ‐) related
genes in different brain regions and used them to construct a novel DNA methylation‐based …

[HTML][HTML] DNA methylation in schizophrenia: progress and challenges of epigenetic studies

M Nishioka, M Bundo, K Kasai, K Iwamoto - Genome medicine, 2012 - Springer
Schizophrenia is a severe psychiatric disease affecting about 1% of the world's population,
with significant effects on patients and society. Genetic studies have identified several …

Hyper-coordinated DNA methylation is altered in schizophrenia and associated with brain function

J Chen, K Schwarz, Z Zang, U Braun… - Schizophrenia …, 2021 - academic.oup.com
DNA methylation is an epigenetic biological process that is emerging as an important
mediator of environmental risk effects on the susceptibility of severe illness, such as …