Analyzing DNA methylation patterns in Schizophrenic patients using machine learning methods
B Torabi Moghadam, M Etemadikhah, G Rajkova… - 2017 - diva-portal.org
Schizophrenia is common mental disorder with known genetic component involved. Since
the association of environmental factors and schizophrenia has been reported, we analyzed …
the association of environmental factors and schizophrenia has been reported, we analyzed …
Analyzing DNA methylation patterns in subjects diagnosed with schizophrenia using machine learning methods
BT Moghadam, M Etemadikhah, G Rajkowska… - Journal of psychiatric …, 2019 - Elsevier
Schizophrenia is a common mental disorder with high heritability. It is genetically complex
and to date more than a hundred risk loci have been identified. Association of environmental …
and to date more than a hundred risk loci have been identified. Association of environmental …
Investigating DNA Methylation Changes Associated With Schizophrenia Using a Family-Based Approach
M Gaine, T Nickl-Jockschat… - Biological …, 2020 - biologicalpsychiatryjournal.com
Background Numerous genetic and environmental factors increase the complexity of
schizophrenia. These factors have the potential to cause systemic pathophysiological …
schizophrenia. These factors have the potential to cause systemic pathophysiological …
[HTML][HTML] Epigenetic profiling of human brain differential DNA methylation networks in schizophrenia
SA Lee, KC Huang - BMC medical genomics, 2016 - Springer
Background Epigenetics of schizophrenia provides important information on how the
environmental factors affect the genetic architecture of the disease. DNA methylation plays a …
environmental factors affect the genetic architecture of the disease. DNA methylation plays a …
Differential DNA methylation and network analysis in schizophrenia
HK Chuan - Computational epigenetics and diseases, 2019 - Elsevier
Schizophrenia is a multidimensional disorder, where a network analysis may be necessary
to create a better understanding on its etiology. Methods for DNA methylation of …
to create a better understanding on its etiology. Methods for DNA methylation of …
Genome-wide methylation profiling of schizophrenia
B Rukova, R Staneva, S Hadjidekova… - Balkan Journal of …, 2014 - sciendo.com
Schizophrenia is one of the major psychiatric disorders. It is a disorder of complex
inheritance, involving both heritable and environmental factors. DNA methylation is an …
inheritance, involving both heritable and environmental factors. DNA methylation is an …
Functional analysis of evolutionary human methylated regions in schizophrenia patients
N Banerjee, T Polushina, AK Stavrum, VM Steen… - bioRxiv, 2019 - biorxiv.org
Background Recent studies have implicated variations in DNA methylation in the aetiology
of schizophrenia. Genome-wide scans in both brain and blood report differential methylated …
of schizophrenia. Genome-wide scans in both brain and blood report differential methylated …
A novel schizophrenia diagnostic model based on statistically significant changes in gene methylation in specific brain regions
D Zou, Y Qiu, R Li, Y Meng, Y Wu - BioMed Research …, 2020 - Wiley Online Library
Objective. The present study identified methylation patterns of schizophrenia‐(SCZ‐) related
genes in different brain regions and used them to construct a novel DNA methylation‐based …
genes in different brain regions and used them to construct a novel DNA methylation‐based …
[HTML][HTML] DNA methylation in schizophrenia: progress and challenges of epigenetic studies
Schizophrenia is a severe psychiatric disease affecting about 1% of the world's population,
with significant effects on patients and society. Genetic studies have identified several …
with significant effects on patients and society. Genetic studies have identified several …
Hyper-coordinated DNA methylation is altered in schizophrenia and associated with brain function
DNA methylation is an epigenetic biological process that is emerging as an important
mediator of environmental risk effects on the susceptibility of severe illness, such as …
mediator of environmental risk effects on the susceptibility of severe illness, such as …