實驗背景: 血清素為一內生性之單胺, 其受體包含有十四種亞型. 多樣並廣泛分布的受器讓血清素
在中樞神經系統及周邊組織參與許多生理調控及病理發展, 因此近年來許多研究以血清素及血清 …

1 In addition to nitric oxide (NO) and prostacyclin (PGI2) an endothelium‐derived factor,
which hyperpolarizes vascular smooth muscle cells via activation of K+ channels …

A significant endothelium-dependent dilation to various stimuli persists in many arterial beds
after the inhibition of nitric oxide synthase (NOS) and cyclo-oxygenase (COX). This …

Previous bioassays of endothelium‐derived hyperpolarizing factor (EDHF) were partially
related to the residual nitric oxide (NO) resistant to NO synthase inhibitors. Further, the role …

Endothelium-derived hyperpolarizing factor (EDHF) is the third factor released by en-
dothelial cell other than NO and PGI2. It relaxes smooth muscle accompanied by a …

In coronary resistance vessels, endothelium-derived hyperpolarizing factor (EDHF) plays an
important role in endothelium-dependent vasodilation. EDHF has been proposed to be …

Several investigations performed in vitro have shown that vascular endothelia can release
diffusible compounds capable of inducing hyperpolarization of the smooth muscle fibers …

In the rat hepatic artery, the endothelium‐derived hyperpolarizing factor (EDHF) was
identified as potassium. Potassium hyperpolarizes the smooth muscles by gating inward …

Introduction: Diabetes mellitus is associated with endothelial dysfunction and which is
believed to result in impaired regulation of vasoconstrictors and vasodilators. Cytochrome …

In addition to NO and prostacyclin, endothelial cells release a factor that elicits
vasodilatation by hyperpolarizing the underlying vascular smooth muscle cells. In some …