[HTML][HTML] Role of Cyp19a1 in the female pathway of a freshwater turtle species (Mauremys reevesii) with temperature-dependent sex determination

PF Wu, XF Wang, F Gao, WG Du - Zoological Research, 2022 - ncbi.nlm.nih.gov
The molecular mechanisms underpinning temperaturedependent sex determination (TSD)
in reptiles have attracted great biological interest for many years. However, which genetic …

Cloning and expression of aromatase in a turtle with temperature-dependent sex determination

C Murdock, T Wibbels - General and comparative endocrinology, 2003 - Elsevier
It has been hypothesized that estrogen production may play a pivotal role in the sex
determination of reptiles with temperature-dependent sex determination (TSD). This …

[HTML][HTML] Epigenetic Control of Gonadal Aromatase (cyp19a1) in Temperature-Dependent Sex Determination of Red-Eared Slider Turtles

Y Matsumoto, A Buemio, R Chu, M Vafaee, D Crews - PLoS One, 2013 - journals.plos.org
In the red-eared slider turtle (Trachemys scripta), a species with temperature-dependent sex
determination (TSD), the expression of the aromatase gene during gonad development is …

[HTML][HTML] Temperature Shift Alters DNA Methylation and Histone Modification Patterns in Gonadal Aromatase (cyp19a1) Gene in Species with Temperature-Dependent …

Y Matsumoto, B Hannigan, D Crews - PLoS One, 2016 - journals.plos.org
The environment surrounding the embryos has a profound impact on the developmental
process and phenotypic outcomes of the organism. In species with temperature-dependent …

Genetic polymorphisms in aromatase (cyp19a1) are not associated with gonadal phenotypes in red-eared slider turtle hatchlings developed at a pivotal temperature

Y Matsumoto, D Crews - Sexual Development, 2017 - karger.com
Embryonic gonad sex in many reptilian species is determined by the incubation temperature
of the egg, a differentiation process known as temperature-dependent sex determination …

Temperature and non-aromatizable androgens: a common pathway in male sex determination in a turtle with temperature-dependent sex determination?

D Crews, AR Cantu, JM Bergeron - Journal of Endocrinology, 1996 - joe.bioscientifica.com
This study addressed the hypothesis that, in the red-eared slider turtle, Trachemys scripta,
non-aromatizable androgens are the physiological equivalent of temperature in determining …

Action of sex steroid hormones on temperature-induced sex determination in the snapping turtle (Chelydra serpentina)

D Crews, T Wibbels, WHN Gutzke - General and Comparative …, 1989 - Elsevier
Administration of exogenous estradiol benzoate (EB) or an estrogen agonist, R2858, into
eggs of snapping turtles caused all embryos incubated at male-producing temperatures to …

Effects of incubation temperature on the expression of sex-related genes in the Chinese pond turtle, Mauremys reevesii

WQ Tang, Y Mu, N Valenzuela, WG Du - Sexual Development, 2018 - karger.com
Despite widespread temperature-dependent sex determination (TSD) in reptiles, it is still
unclear how the molecular network responds to temperature variation and drives the sexual …

Embryological ontogeny of aromatase gene expression in Chrysemys picta and Apalone mutica turtles: comparative patterns within and across temperature …

N Valenzuela, T Shikano - Development genes and evolution, 2007 - Springer
Although the role of aromatase in many estrogen-dependent reproductive and metabolic
functions is well documented in vertebrates, its involvement in the ovarian development of …

Loss- and gain-of-function analyses reveal the essential role of Cyp19a1 in ovarian determination of the red-eared slider turtle

J Shen, W Sun, K Wu, T Zhuang, J Lei, Q Ma, L Xiao… - Genetics, 2023 - academic.oup.com
Estrogen signaling exerts a decisive role in female sex determination and differentiation in
chicken and fish. Aromatase encoded by Cyp19a1 is the key enzyme that catalyzes the …