Expression of P450arom in Malaclemys terrapin and Chelydra serpentina: A tale of two sites

AR Place, J Lang, S Gavasso… - Journal of Experimental …, 2001 - Wiley Online Library
The formation of estrogens from androgens in all vertebrates is catalyzed by the “aromatase”
complex, which consists of a membrane bound P450 enzyme, P450 aromatase (which binds …

[引用][C] The effect of the Cyp19a1 gene methylation modification on temperature-dependent sex determination of Reeves' turtle (Mauremys reevesii)

W Ru, L Hua, Y Wei, W Li, D Cao, Y Ge, H Chen, X Lan… - Asian Herpetol. Res, 2017

Characterization and expression profile of the ovarian cytochrome P‐450 aromatase (cyp19A1) gene during thermolabile sex determination in pejerrey, Odontesthes …

M Karube, JI Fernandino… - … Zoology Part A …, 2007 - Wiley Online Library
Abstract Cytochrome P450 aromatase (cyp19) is an enzyme that catalyzes the conversion of
androgens to estrogens and may play a role in temperature‐dependent sex determination …

Temperature-dependent sex determination in the snapping turtle: manipulation of the embryonic sex steroid environment

T Rhen, JW Lang - General and Comparative Endocrinology, 1994 - Elsevier
In certain reptiles with temperature-dependent sex determination (TSD), estrogens act as a
signal for female differentiation. Because aromatase produces estrogens from androgens …

Potential role of DNA methylation of cyp19a1a promoter during sex change in protogynous orange-spotted grouper, Epinephelus coioides

CY Guo, PW Tseng, JS Hwang, GC Wu… - General and Comparative …, 2021 - Elsevier
Estrogen has a pivotal role in early female differentiation and further ovarian development.
Aromatase (Cyp19a) is responsible for the conversion of androgens to estrogens in …

Endocrine sex reversal of gonads by the aromatase inhibitor Letrozole (CGS 20267) in Emys orbicularis, a turtle with temperature-dependent sex determination

N Richard-Mercier, M Dorizzi, G Desvages… - General and …, 1995 - Elsevier
In embryos of Emys orbicularis, the sexual differentiation of gonads is influenced by the
incubation temperature of eggs. Estrogens administered during the thermosensitive period …

Expression and characterization of the cyp19a gene and its responses to estradiol/letrozole exposure in Chinese soft‐shelled turtle (Pelodiscus sinensis)

HW Liang, Y Meng, LH Cao, X Li… - Molecular reproduction …, 2019 - Wiley Online Library
Abstract Cytochrome P450 aromatase (CYP19) catalyzes the conversion of androgens to
estrogens and is critical in sex differentiation. CYP19 exists as the ovarian type and brain …

Exogenous application of estradiol to eggs unexpectedly induces male development in two turtle species with temperature-dependent sex determination

DA Warner, E Addis, W Du, T Wibbels… - General and comparative …, 2014 - Elsevier
Steroid hormones affect sex determination in a variety of vertebrates. The feminizing effects
of exposure to estradiol and the masculinizing effects of aromatase inhibition during …

Sensitive stages for the effects of temperature on gonadal aromatase activity in embryos of the marine turtle Dermochelys coriacea

G Desvages, M Girondot, C Pieau - General and comparative …, 1993 - Elsevier
Many data suggest an involvement of estrogens in gonadal differentiation in reptiles with
temperature-dependent sex determination (TSD). However, the site of estrogen synthesis in …

The ovary retains male potential after the thermosensitive period for sex determination in the turtle Emys orbicularis

M Dorizzi, N Richard-Mercier, C Pieau - Differentiation, 1996 - Elsevier
Emys orbicularis is a turtle with temperature-dependent sex determination. The
thermosensitive period (TSP) lies between embryonic stages 16 and 22. Gonadal …