Neurovascular disorders, such as traumatic brain injury and stroke, persist as leading
causes of death and disability–thus, the search for novel therapeutic approaches for these …

Neurovascular disorders, such as traumatic brain injury and stroke, persist as leading
causes of death and disability–thus, the search for novel therapeutic approaches for these …

Therapeutic hypothermia has consistently been shown to be a robust neuroprotectant in
many labs studying different models of neurological disease. Although this therapy has …

Stroke is a leading cause of disability and death, yet effective treatments for acute stroke has
been very limited. Thus far, tissue plasminogen activator has been the only FDA-approved …

Therapeutic hypothermia, or cooling of the body or brain for the purposes of preserving
organ viability, is one of the most robust neuroprotectants at both the preclinical and clinical …

Three decades of animal studies have reproducibly shown that hypothermia is profoundly
cerebroprotective during or after a central nervous system (CNS) insult. The success of …

Cerebral ischemia is a serious dynamic event in the brain involving heterogeneous cell
types. Neuroprotective agents represent a potential approach for the treatment of acute …

Stroke is a leading threat to human life and health in the US and around the globe, while
very few effective treatments are available for stroke patients. Preclinical and clinical studies …

Hypothermia has emerged as a viable neuroprotectant at the clinical level. The reasons for
its protective effect are likely due to its ability to affect multiple facets of ischemic brain injury …

Hypothermia is considered as a promising neuroprotective treatment for ischemic stroke but
with many limitations. To expand its clinical relevance, this study evaluated the combination …