Correlation of 18F-FDG-PET/CT metabolic parameters with PD-L1 tumour proportion score (TPS) in resected non-small cell lung cancer (NSCLC)

D Hughes, S Hunter, D Nonaka, V Goh, A Bille… - Lung …, 2021 - kclpure.kcl.ac.uk
Introduction: Immune checkpoint inhibitors targeting the PD-1/PD-L1 axis play a significant
role in the adjuvant and metastatic treatment of non-small cell lung cancer (NSCLC). PD-L1 …

1161P Can 18F-FDG-PET/CT predict PD-L1 expression in resected non-small cell lung cancer (NSCLC)?

DJ Hughes, S Hunter, D Nonaka, V Goh… - Annals of …, 2021 - annalsofoncology.org
Background Anti-PD-(L) 1 agents play an important role in the management of NSCLC. PD-
L1 analysis by immunohistochemistry is an important biomarker but displays temporospatial …

1283P Predicting PD-L1 expression using [18F] FDG PET/CT in early stage non-small cell lung cancer (NSCLC)

DJ Hughes, E Josephides, R O'Shea… - Annals of …, 2023 - annalsofoncology.org
Background Advances in the management of early stage NSCLC include the introduction of
PD-1/PD-L1 checkpoint inhibitors. PD-L1 is an important biomarker but its role in early …

18F-FDG PET metabolic-to-morphological volume ratio predicts PD-L1 tumour expression and response to PD-1 blockade in non-small-cell lung cancer

M Jreige, I Letovanec, K Chaba, S Renaud… - European journal of …, 2019 - Springer
Abstract Purpose Anti-PD-1/PD-L1 blockade can restore tumour-specific T-cell immunity and
is an emerging therapy in non-small-cell lung cancer (NSCLC). We investigated the …

Correlation of metabolic information on FDG-PET with tissue expression of immune markers in patients with non-small cell lung cancer (NSCLC) who are candidates …

E Lopci, L Toschi, F Grizzi, D Rahal, L Olivari… - European journal of …, 2016 - Springer
Purpose Eliciting antitumor T-cell response by targeting the PD-1/PD-L1 axis with
checkpoint inhibitors has emerged as a novel therapeutic strategy in non-small cell lung …

Comparison of metabolic parameters of Ga-68 FAPI PET/CT and F-18 FDG PET/CT with PD L-1 expression in non-small cell lung cancer

R Kumar, P Purohit, B Mittal, H Singh, J Shukla, A Bal… - 2024 - Soc Nuclear Med
241943 Introduction: Lung cancer is one of the most common cancers, causing significant
morbidity and mortality. F-18 FDG PET/CT has a proven value in diagnosing and staging …

Predicting programmed death-ligand 1 (PD-L1) expression with fluorine-18 fluorodeoxyglucose ([18F]FDG) positron emission tomography/computed tomography …

DJ Hughes, E Josephides, R O'Shea… - European …, 2024 - Springer
Background Programmed death-ligand 1 (PD-L1) expression is a predictive biomarker for
immunotherapy in non-small cell lung cancer (NSCLC). PD-L1 and glucose transporter 1 …

PD-L1 expression correlation with metabolic parameters of FDG PET/CT and clinicopathological characteristics in non-small cell lung cancer

X Wu, Y Huang, Q Zhao, L Wang, X Song, Y Li… - EJNMMI research, 2020 - Springer
Background Immunotherapy targeting programmed cell death 1 (PD-1) or its ligand 1 (PD-
L1) has shown promising results in non-small cell lung cancer (NSCLC) patients. Exploring …

Combining PD-L1 expression and standardized uptake values in FDG-PET/CT can predict prognosis in patients with resectable non–small-cell lung cancer

T Miyazawa, K Otsubo, H Sakai, H Kimura… - Cancer …, 2021 - journals.sagepub.com
Background This study aimed to determine the relationship of programmed death-ligand 1
(PD-L1) expression and standardized uptake values in fluorodeoxyglucose–positron …

PD-L1 expression correlation with metabolic parameters of 18F-FDG PET/CT in nonsmall cell lung cancer

E Akgun, R Akyel, AS Koç, B Demirkol, PA Kabalak… - Médecine Nucléaire, 2024 - Elsevier
Objective The aim of this study is to evaluate correlation between Programmed cell death
ligand 1 (PD-L1) mutation status with metabolic parameters derived from 18-F Fluoro-2 …