Background Metabolic syndrome is an important side effect associated with clozapine. It has
been hypothesized that weight gain contributes to the development of metabolic syndrome …

Method: This study is a retrospective cohort study combining a cross-sectional survey of
metabolic syndrome and retrospective chart review. The subjects were hospitalized …

Objective: This study compared the prevalence of the metabolic syndrome among
outpatients with schizophrenia and schizoaffective disorder receiving clozapine with a …

The purpose of this pilot study is to determine if an association exists between clozapine-
associated weight gain and resting metabolic rate (RMR). In doing so, we used a “pretest …

Objectives Weight gain on clozapine is highly variable and poorly predictable. Its
mechanisms are not well understood. This study explores the factors that predict weight gain …

Objective: The aim of this study was to assess the prevalence and magnitude of weight
changes pre-and post-clozapine and to explore the ability of demographic and clinical …

The article discusses research which evaluated the effects of clozapine dose on weight,
blood pressure and metabolic parameters including lipids and glucose in a group of …

Objective Clozapine is the first choice in drug-resistant schizophrenia but also causes
important weight changes. This might discourage clinicians who are concerned about the …

OBJECTIVE: This study was designed to investigate the effects of long term clozapine
treatment on changes of weight, glucose and cholesterol levels and their relation to …

Background: Metabolic syndrome (obesity, glucose intolerance, insulin resistance and
dyslipidaemia) is a well-known adverse effect of most antipsychotics. It is particularly …