Schizophrenia has a prevalence of 1 percent in all cultures and is equally common in men
and women. It is a devastating mental illness that impairs mental and social functioning …

Objective: Obese patients with schizophrenia being treated with clozapine and non-
psychiatric obese are often assumed to share the same physiological changes in obesity …

Objective: Patients with schizophrenia treated with clozapine often gain weight. This study
evaluated the effects of dietary control and physical activity among obese inpatients with …

Introduction: Schizophrenia is a chronic mental disorder, and treatment is based on the use
of antipsychotics, such as clozapine. These drugs have been associated with obesity and …

OBJECTIVE: This study was designed to investigate the effects of long term clozapine
treatment on changes of weight, glucose and cholesterol levels and their relation to …

Background Metabolic syndrome is an important side effect associated with clozapine. It has
been hypothesized that weight gain contributes to the development of metabolic syndrome …

Increase in body weight was observed in more than 50% of schizophrenic patients who
receive antipsychotic drugs in general. 8 Body mass index (BMI) is significantly higher in …

Over the last three decades, an epidemic of obesity has markedly affected patients suffering
from mental illnesses such as schizophrenia. Antipsychotic medications used to treat …

Background: Both obesity and smoking are common in schizophrenia patients taking
clozapine, causing cardiovascular disease and premature deaths. Methods: Two hundred …

Objective: This study sought to examine the effectiveness of sibutramine, a weight loss
agent, on clozapine‐associated weight gain. Method: This was a 12‐week double‐blind …