改变新陈代谢以延长寿命
J Pessoa, AI Duarte - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
Due to their intense electrical activity, neurons have high energy demands. This requirement
makes them particularly sensitive to mitochondrial dysfunction. Like all eukaryotic cells …
makes them particularly sensitive to mitochondrial dysfunction. Like all eukaryotic cells …
[HTML][HTML] Overcoming mitochondrial dysfunction in neurodegenerative diseases
J Pessoa, AI Duarte - Neural regeneration research, 2023 - journals.lww.com
Due to their intense electrical activity, neurons have high energy demands. This requirement
makes them particularly sensitive to mitochondrial dysfunction. Like all eukaryotic cells …
makes them particularly sensitive to mitochondrial dysfunction. Like all eukaryotic cells …
靶向线粒体认为神经退行性变通路的新治疗策略
D Trigo, JJ Vitória, OABC e Silva - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
In recent years, multiple disciplines have focused on mitochondrial biology and contributed
to understanding its relevance towards adult-onset neurodegenerative disorders. These are …
to understanding its relevance towards adult-onset neurodegenerative disorders. These are …
调节神经元生物能是治疗神经退行性疾病的潜在策略
IG Onyango, JP Bennett Jr, GB Stokin - 中国神经再生研究(英文版), 2021 - sjzsyj.com.cn
Neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease,
Huntington's disease, and amyotrophic lateral sclerosis are a heterogeneous group of …
Huntington's disease, and amyotrophic lateral sclerosis are a heterogeneous group of …
[HTML][HTML] Relationships between mitochondrial dysfunction and neurotransmission failure in Alzheimer's disease
Besides extracellular deposition of amyloid beta and formation of phosphorylated tau in the
brains of patients with Alzheimer's disease (AD), the pathogenesis of AD is also thought to …
brains of patients with Alzheimer's disease (AD), the pathogenesis of AD is also thought to …
[HTML][HTML] Mitochondrial Dysfunction and Alzheimer's Disease
N Nasim - aggietranscript.ucdavis.edu
Author's note: Based on my interest in exploring Alzheimer's pathology, I have been
interested in the molecular mechanisms that drive neurodegeneration. After working on a …
interested in the molecular mechanisms that drive neurodegeneration. After working on a …
[HTML][HTML] Mitochondrial dysfunction as a target in neurodegenerative diseases
L Perrone - Frontiers in Molecular Neuroscience, 2023 - frontiersin.org
The factors underlying the onset and progression of neurodegeneration are not yet fully
elucidated, resulting in difficulties for the development of therapeutic strategies aimed to …
elucidated, resulting in difficulties for the development of therapeutic strategies aimed to …
Mitochondrial decay, a major cause of aging, can be delayed
BN Ames - Journal of Alzheimer's Disease, 2004 - content.iospress.com
Mitochondrial decay due to oxidant byproducts is a principal underlying contributor to aging,
including the degenerative diseases of aging such as brain degeneration [15, 23, 32]. The …
including the degenerative diseases of aging such as brain degeneration [15, 23, 32]. The …
The role of mitochondrial dysfunction in Alzheimer's disease: a potential pathway to treatment
AB Reiss, S Ahmed, C Dayaramani, AD Glass… - Experimental …, 2022 - Elsevier
Background Alzheimer's disease (AD) is the most prevalent form of dementia worldwide and
is characterized by progressive memory loss and cognitive impairment. Our understanding …
is characterized by progressive memory loss and cognitive impairment. Our understanding …
[PDF][PDF] Mitochondria: Strategic point in the field of Alzheimer's disease
SJ Baloyannis - Journal of Alzheimers and …, 2016 - pdfs.semanticscholar.org
Alzheimer's disease is the most common cause of age-dependent cognitive decline
composing a tragic epilogue in senility. A substantial number of cellular and biochemical …
composing a tragic epilogue in senility. A substantial number of cellular and biochemical …