本研究以反應性醛與極性麻醉物氯酚針對Microtox 進行混合毒性試驗, 並引用Christensen &
Chen 混合毒性理論預測其混合毒性變化. Microtox 混合毒性實驗結果大致符合非交互作用混合 …

本研究針對反應性類毒性物質-醛類與腈類, 以及極性麻醉毒性物質-含鹵素取代基苯胺,
以Microtox 生物試驗進行混合毒性試驗, 實驗結果顯示, 此兩類不同機制的毒性物質混合後 …

Lidocaine이 Cisatracurium의 용량-반응곡선에 미치는 영향 Page 1 대한마취과학회지 2002; 42:
351∼354 351 Lidocaine이 Cisatracurium의 용량-반응곡선에 미치는 영향 울산대학교 의과대학 …

With the spread of total intravenous anesthesia, clinical pharmacology has become more
important. We report Microsoft Excel file applying three compartment model and response …

Dose–frequency curves of toxic effects of a substance A were evaluated in the absence and
in the presence of a fixed dose of a second substance B. Data were fitted by the curve–fitting …

The relative potencies of propofol and thiopentone were assessed using different indicators
of induction of anaesthesia: abolition of the response to verbal commands and eyelash …

In rat experiments, the dose-effect curves for three different end points of anesthesia [loss of
righting reflex (RR), prevention of movement (PM), and heart rate response (HR) to noxious …

Purpose To test the hypothesis that the MAC values of nitrous oxide (N 2 O) and isoflurane
were not linearly additive, as theorized by the postulated mode of action based on lipid …

A quantitative structure‐toxicology (LD50) relationship for some N‐alkylsuccinimides is
presented. The relationship is based on a small and carefully selected training set using …

Background The non-linear mixed amount with zero amounts response surface model can
be used to describe drug interactions and predict loss of response to noxious stimuli and …