Tumor epigenetics is a new subject, mainly including DNA methylation, histone modification
and chromatin remodeling, genomic imprinting and the coding RNA control, etc. Among …

DNA methylation is a kind of epigenetic modification in human genome. Both
hypermethlation of tumor suppressor gene or DNA repair gene and hypomethylation of …

DNA methylation is a kind of epigenetic modification in human genome. Both
hypermethylation of tumor suppressor gene or DNA repair gene and hypomethylation of …

DNA methylation is an important conception in the studies of biology and medicine. Analysis
of DNA methylation is one of major strategies and techniques for carcinogenesis. In this …

DNA methylation is an important and reversible epigenetic modification which regulates
genomic stability. Methylation is essential for mammalian development. Generally, gene …

All kinds of tumors have their specific DNA methylation patterns. The study of DNA
methylation changes in chronic myelogenous leukemia includes (1) the hypomethylation of …

细胞癌变是一个多阶段复杂过程, 它包括原癌基因的激活和抑癌基因的失活,
并涉及基因和基因外的多种改变. 近来, 人们发现肿瘤细胞的总体甲基化水平低于正常细胞 …

表遗传学(epigenetics) 调节与肿瘤相关基因的转录调控密切相关. DNA 甲基化就是基因表遗传
学调节的重要机制之一. DNA 异常甲基化与肿瘤的发生和演进关系密切, 而DNA …

Leukemia is a malignant hematopoietic disease with clonal proliferation of hematopoietic
cells, which seriously threatens the lives of patients. DNA methylation is an important …

DNA methylation is one of the main epigenetic modifications. It controls gene expression
through altering chromosomal structure, DNA conformation, DNA stability and the function …