In Vivo Antitumor Effect of CD40L-transduced Tumor Cells as a Vaccine for B-Cell Lymphoma
J Briones, J Timmerman, R Levy - Cancer research, 2002 - AACR
Abstract CD40-CD40 ligand (CD40L) interactions play a critical role in the activationof
cellular immunity. CD40L enhances the antigen presentation function of CD40-expressing B …
cellular immunity. CD40L enhances the antigen presentation function of CD40-expressing B …
Anti-tumor immunity induced by in vivo adenovirus vector-mediated expression of CD40 ligand in tumor cells
T Kikuchi, RG Crystal - Human gene therapy, 1999 - liebertpub.com
CD40 ligand (CD40L), the ligand for CD40 on antigen-presenting cells, is essential for the
initiation of antigen-specific T cell responses, an important component of the immune …
initiation of antigen-specific T cell responses, an important component of the immune …
In vivo gene transfer of CD40 ligand into colon cancer cells induces local production of cytokines and chemokines, tumor eradication and protective antitumor …
Y Sun, D Peng, J Lecanda, V Schmitz, M Barajas… - Gene therapy, 2000 - nature.com
The interaction between CD40 ligand (CD40L, CD154) and its receptor CD40 on antigen-
presenting cells, is essential for the initiation of cell-mediated and humoral immune …
presenting cells, is essential for the initiation of cell-mediated and humoral immune …
Therapeutic vaccination against murine lymphoma by intratumoral injection of recombinant fowlpox virus encoding CD40 ligand
A Liu, A Guardino, L Chinsangaram, MJ Goldstein… - Cancer research, 2007 - AACR
The interaction between CD40 ligand (CD40L, CD154) and its receptor CD40 on antigen-
presenting cells is essential for the initiation of cell-mediated and humoral immune …
presenting cells is essential for the initiation of cell-mediated and humoral immune …
T-cell-dependent antitumor effects produced by CD40 ligand expressed on mouse lung carcinoma cells are linked with the maturation of dendritic cells and secretion …
Y Tada, L Yu, O Shimozato, YQ Wang… - Cancer Gene …, 2003 - nature.com
Abstract CD40/CD40 ligand (CD40L) interaction plays an essential role in cell-mediated
immune responses. We examined whether expression of CD40L in murine lung carcinoma …
immune responses. We examined whether expression of CD40L in murine lung carcinoma …
Transgenic expression of CD40L and interleukin-2 induces an autologous antitumor immune response in patients with non-Hodgkin's lymphoma
S Takahashi, P Yotnda, RF Rousseau, Z Mei… - Cancer gene …, 2001 - nature.com
The malignant B cells of non-Hodgkin's lymphoma (B-NHL cells) express peptides derived
from tumor-specific antigens such as immunoglobulin idiotypes, and also express major …
from tumor-specific antigens such as immunoglobulin idiotypes, and also express major …
Antitumor effect of CD40 ligand: elicitation of local and systemic antitumor responses by IL-12 and B7
A Nakajima, T Kodama, S Morimoto… - The Journal of …, 1998 - journals.aai.org
The interaction between CD40 ligand (CD40L, CD154) and its receptor CD40 has been
implicated in the establishment of cell-mediated immunity as well as humoral immune …
implicated in the establishment of cell-mediated immunity as well as humoral immune …
Antitumor immunity against bladder cancer induced by ex vivo expression of CD40 ligand gene using retrovirus vector
T Kimura, T Ohashi, T Kikuchi, H Kiyota, Y Eto… - Cancer Gene …, 2003 - nature.com
The interaction between CD40 ligand (CD40L) and CD40 on antigen-presenting cells is
essential for the initiation of antigen-specific T-cell responses. In order to clarify whether the …
essential for the initiation of antigen-specific T-cell responses. In order to clarify whether the …
Antitumor responses induced by transgenic expression of CD40 ligand
ME Grossmann, MP Brown, MK Brenner - Human gene therapy, 1997 - liebertpub.com
ABSTRACT Because CD40 ligand (CD40L) is a co-stimulator molecule for multiple
components of the immune response, we wanted to determine whether transgenic …
components of the immune response, we wanted to determine whether transgenic …
Improved immunogenicity of a self tumor antigen by covalent linkage to CD40 ligand
HI Huang, PY Wu, CY Teo, MN Chen… - … journal of cancer, 2004 - Wiley Online Library
The interaction between the CD40 ligand (CD40L) and CD40 on antigen‐presenting cells
(APCs) is critical in promoting humoral and cellular immune responses. Agonistic anti‐CD40 …
(APCs) is critical in promoting humoral and cellular immune responses. Agonistic anti‐CD40 …