背景: JAG1 是Notch 訊息傳遞的重要因子, 前人研究已經證實Notch 訊息傳遞路徑可以用來調控
癌症細胞的分化與生長, 近期的研究更指出JAG1 與癌症的轉移有所關聯, 因此我們的目標是要 …

背景: JAG1 是Notch 訊息傳遞的重要因子, 前人研究已經證實Notch 訊息傳遞路徑可以用來調控
癌症細胞的分化與生長, 近期的研究更指出JAG1 與癌症的轉移有所關聯, 因此我們的目標是要 …

JAG1 is a Notch ligand that plays a critical role in multiple signaling pathways. However, the
functionality of JAG1 in non-small cell lung cancer (NSCLC) has not been investigated …

Jagged canonical Notch ligand 1 (JAG1) regulates the progression of many cancers by the
Notch signaling pathway, but its role in breast cancer (BC) remains unclear. In this research …

Background: The notch pathway is involved in control of cell differentiation in various tissues
including pancreas, muscle and bone marrow. Jagged 2 (JAG2) is a ligand for the notch …

Abstract 2168 Notch3 (N3) is a member of the family of Notch transmembrane receptors,
which are activated by ligands such as Jagged1 (JAG1). In addition to roles in normal …

Breast cancer (BC) patients have better outcomes when cancer is detected early, but
metastasis remains a major cause of mortality. High levels of the Notch ligand JAGGED-1 …

The Notch signaling pathway is deregulated in numerous solid types of cancer including
non-small cell lung cancer (NSCLC). However, the profile of Notch ligand expression …

Non-small cell lung cancer (NSCLC) accounts for 85% of new lung cancer diagnoses and
patients diagnosed with the disease typically have poor prognoses. Intratumoral …

Objectives JAG2 is one of Notch ligands, which recently appear to exert various
carcinogenesis. In the present study, we aimed to unveil the relation of JAG2 expression and …