关于MxA 蛋白抗病毒作用及其机制的研究进展
黄琴， 许红梅 - 重庆医科大学学报, 2007 - cqvip.com
MxA 蛋白是由Ⅰ 型干扰素(IFN-α/β) 诱导产生的, 属于动态蛋白超家族的一类大分子GTPase,
除了具有这一类蛋白的共性外, 其最大的, 独有的特性在于: 对于一系列RNA 病毒, 双链DNA …
除了具有这一类蛋白的共性外, 其最大的, 独有的特性在于: 对于一系列RNA 病毒, 双链DNA …
New Sandwich‐Type Enzyme‐Linked Immunosorbent Assay for Human MxA Protein in a Whole Blood Using Monoclonal Antibodies Against GTP‐Binding Domain for …
M Kawamura, A Kusano, A Furuya… - Journal of clinical …, 2012 - Wiley Online Library
Objectives To develop a clinically significant and practical enzyme‐linked immunosorbent
assay (ELISA) for the detection of MxA protein in human whole blood, a biological marker of …
assay (ELISA) for the detection of MxA protein in human whole blood, a biological marker of …
[PDF][PDF] 免疫共沉淀筛选细胞内与A 型流感病毒M2 蛋白相互作用的蛋白
李耀东， 关振宏， 严景华 - 微生物学报, 2009 - researchgate.net
目的筛选细胞内与A 型流感病毒M2 蛋白(AM2) 相互作用的蛋白质. 方法将AM2
编码序列插入真核表达载体pCAGGS-CFlag, 重组质粒pCAGGS-CFlag-AM2 转染HEK-293T …
编码序列插入真核表达载体pCAGGS-CFlag, 重组质粒pCAGGS-CFlag-AM2 转染HEK-293T …
[HTML][HTML] Expression of MxA protein in blood lymphocytes discriminates between viral and bacterial infections in febrile children
M Halminen, J Ilonen, I Julkunen, O Ruuskanen… - Pediatric …, 1997 - nature.com
Interferons (IFNs), which are induced by viruses, form an essential part of host's defense
systems against viral infections. The antiviral actions of IFNs are mediated by several IFN …
systems against viral infections. The antiviral actions of IFNs are mediated by several IFN …
[引用][C] 野生型MxA 蛋白及其突变体抑制HBV 复制活性研究
余治健 - 2008 - 万方数据资源系统
研究背景: MxA 蛋白由662 个氨基酸残基组成, 是大GTP 酶蛋白超家族成员和动力素超家族成员
, 分子量为76KD. MxA 蛋白有GTP 酶活性, 即该蛋白有结合GTP 的活性和水解GTP 能力. MxA …
, 分子量为76KD. MxA 蛋白有GTP 酶活性, 即该蛋白有结合GTP 的活性和水解GTP 能力. MxA …
MxA 抗病毒蛋白的研究进展
冼盈， 张扣兴 - 国际内科学杂志, 2009 - cqvip.com
MxA 抗病毒蛋白是由I 型干扰素(IFNα/β) 诱导产生的分布于细胞质中的蛋白质,
具有广谱的抗病毒作用, 对多种RNA 病毒和部分DNA 病毒均有抑制作用. 活化的MxA …
具有广谱的抗病毒作用, 对多种RNA 病毒和部分DNA 病毒均有抑制作用. 活化的MxA …
MxA GTPase: oligomerization and GTP-dependent interaction with viral RNP target structures
G Kochs, M Trost, C Janzen, O Haller - Methods, 1998 - Elsevier
MxA protein is an interferon-induced GTPase of human cells that inhibits the multiplication of
several RNA viruses, including influenza viruses and bunyaviruses. Studies on MxA …
several RNA viruses, including influenza viruses and bunyaviruses. Studies on MxA …
MX1 proteins and influenza A virus under the microscope
J McKellar, O Moncorgé, C Goujon - Virologie, 2023 - jle.com
a. A549 human epithelial lung cells infected with A/Victoria/3/75 (H3N2) influenza A virus for
24h at multiplicity of infection of 1. Cells were fixed, stained and imaged on a confocal …
24h at multiplicity of infection of 1. Cells were fixed, stained and imaged on a confocal …
Functional comparison of Mx1 from two different mouse species reveals the involvement of loop L4 in the antiviral activity against influenza A viruses
J Verhelst, J Spitaels, C Nürnberger… - Journal of …, 2015 - Am Soc Microbiol
The interferon-induced Mx1 gene is an important part of the mammalian defense against
influenza viruses. Mus musculus Mx1 inhibits influenza A virus replication and transcription …
influenza viruses. Mus musculus Mx1 inhibits influenza A virus replication and transcription …