Improving phosphate-binder therapy as a way forward

AJ Hutchison - Nephrology Dialysis Transplantation, 2004 - academic.oup.com
Aluminium-or calcium-based phosphate-binding agents traditionally have been used to treat
hyperphosphataemia in patients with end-stage renal disease. Although these agents …

Non-calcium-containing phosphate binders: comparing efficacy, safety, and other clinical effects

JM Frazão, T Adragão - Nephron Clinical Practice, 2012 - karger.com
Phosphate-binder therapy for hyperphosphataemia is key to the treatment of patients with
chronic kidney disease (CKD)-mineral and bone disorder (MBD). Calcium-free phosphate …

Lanthanum carbonate effectively controls serum phosphate without affecting serum calcium levels in patients undergoing hemodialysis

T Shigematsu… - Therapeutic …, 2008 - Wiley Online Library
Treating hyperphosphatemia without increasing the calcium load in chronic kidney disease
patients on dialysis is important, as conventional treatment frequently results in ectopic …

Long-term efficacy and safety profile of lanthanum carbonate: results for up to 6 years of treatment

AJ Hutchison, ME Barnett, R Krause, JTC Kwan… - Nephron Clinical …, 2008 - karger.com
Abstract Background/Aims: Lanthanum carbonate (LC, FOSRENOL®) is an effective
phosphate binder for which tolerability and a safety profile have been reported in …

Evolution of bone and plasma concentration of lanthanum in dialysis patients before, during 1 year of treatment with lanthanum carbonate and after 2 years of follow …

GB Spasovski, A Sikole, S Gelev… - Nephrology Dialysis …, 2006 - academic.oup.com
Background. Lanthanum carbonate (LC) has been proposed as a new phosphate binder.
Presented here are the results from one centre that participated in a multicentre trial to …

Lanthanum carbonate: safety data after 10 years

AJ Hutchison, RJ Wilson, S Garafola, JB Copley - Nephrology, 2016 - Wiley Online Library
Despite 10 years of post‐marketing safety monitoring of the phosphate binder lanthanum
carbonate, concerns about aluminium‐like accumulation and toxicity persist. Here, we …

Control of serum phosphate by oral lanthanum carbonate in patients undergoing haemodialysis and continuous ambulatory peritoneal dialysis in a short-term …

F Al-Baaj, M Speake… - Nephrology Dialysis …, 2005 - academic.oup.com
Background. Hyperphosphataemia in dialysis patients is associated with significant
morbidity. We assessed the ability of lanthanum carbonate to control phosphate levels in …

Effect of treating hyperphosphatemia with lanthanum carbonate vs calcium carbonate on cardiovascular events in patients with chronic kidney disease undergoing …

H Ogata, M Fukagawa, H Hirakata, T Kagimura… - Jama, 2021 - jamanetwork.com
Importance Among patients with hyperphosphatemia undergoing dialysis, it is unclear
whether non–calcium-based phosphate binders are more effective than calcium-based …

[HTML][HTML] A multicenter study on the effects of lanthanum carbonate (Fosrenol™) and calcium carbonate on renal bone disease in dialysis patients

PC D'Haese, GB Spasovski, A Sikole, A Hutchison… - Kidney International, 2003 - Elsevier
A multicenter study on the affects of lanthanum carbonate (Fosrenol™) and calcium
carbonate on renal bone disease in dialysis patients. Background Lanthanum carbonate …

[HTML][HTML] Lanthanum carbonate for the treatment of hyperphosphatemia in CKD 5D: multicenter, double blind, randomized, controlled trial in mainland China

J Xu, YX Zhang, XQ Yu, ZH Liu, LN Wang, JH Chen… - BMC nephrology, 2013 - Springer
Background Serum phosphorus control is critical for chronic kidney disease (CKD) 5D
patients. Currently, clinical profile for an oral phosphorus binder in the mainland Chinese …