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[PDF][PDF] What is new in new generation calcium channel blocker

MMR Siddiqui, SSB Mosharraf… - Anwer Khan Modern …, 2019 - academia.edu
Hypertension is a multifactorial and multisystem disease in which elevated blood pressure is
only one sign of multiple underlying physiological abnormalities. It affects approximately …

Determination of cilnidipine, a new calcium antagonist, in human plasma using high performance liquid chromatography with tandem mass spectrometric detection

X Zhang, S Zhai, R Zhao, J Ouyang, X Li… - Analytica chimica …, 2007 - Elsevier
A rapid, sensitive and reliable high performance liquid chromatographic method coupled
with tandem mass spectrometry (HPLC–MS/MS) has been developed and validated for the …

A Comprehensive Insight on Pharmacological Properties of Cilnidipine: A Fourth-generation Calcium Channel Blocker

R Kadian, A Nanda - Cardiovascular & Hematological Agents in …, 2024 - ingentaconnect.com
Preventing the development of cardiovascular problems is a key objective of
antihypertensive drugs. Many of the non-pressure related coronary risk factors for …

Novel crude and crystalline forms of lercanidipine hydrochloride

F Bonifacio, F Campana, G Iasi… - US Patent App. 11 …, 2005 - Google Patents
The invention describes novel lercanidipine crude Forms (A) and (B), novel lercanidipine
hydrochloride crystalline Forms (I) and (II) obtained from said crude Forms, phar maceutical …

Development of a liquid chromatography/negative-ion electrospray tandem mass spectrometry assay for the determination of cilnidipine in human plasma and its …

HW Lee, JH Seo, HS Lee, SY Jeong, YW Cho… - … of Chromatography B, 2008 - Elsevier
A simple method using a one-step liquid–liquid extraction (LLE) with methyl-t-butyl ether
(MTBE) followed by high-performance liquid chromatography (HPLC) with negative-ion …

A Validated Stability Indicating RP-HPLC Method for Quantification of Cilnidipine in Bulk and in Tablet Dosage Form.

R Gholve, S Pekamwar - Oriental Journal of Chemistry, 2021 - search.ebscohost.com
Abstract A stability indicating RP-HPLC method has been developed for quantification of
Cilnidipine in bulk and in tablet dosage form. The chromatographic analysis was …

Novel crude and crystalline forms of lercanidipine hydrochloride

F Bonifacio, F Campana, G Iasi… - US Patent App. 11 …, 2005 - Google Patents
The invention describes novel lercanidipine crude Forms (A) and (B), novel lercanidipine
hydrochloride crystalline Forms (I) and (II) obtained from said crude Forms, phar maceutical …

Novel crude and crystalline forms of lercanidipine hydrochloride

F Bonifacio, F Campana, G Delasi… - US Patent App. 10 …, 2004 - Google Patents
The invention describes novel lercanidipine crude Forms (A) and (B), novel lercanidipine
hydrochloride crystalline Forms (I) and (II) obtained from said crude Forms, phar maceutical …

A Randomized, Open-Label, Two-way Crossover Bioequivalence Study of Cilacar Tablet Compared with Atelec Tablet in Healthy Volunteers Under Fasting Condition

S Salunke, A Naik, S Chaudhari… - Journal of Drug …, 2022 - jddtonline.info
Cilnidipine is a novel L/N type calcium channel blocker, approved in several countries world-
wide for the treatment of hypertension and is also well-established for its varied pleiotropic …