[PDF][PDF] Analytical methodologies for determination of Cilnidipine: An overview

KS Kokilambigai, KS Lakshmi - Int J Pharm Pharm Sci, 2014 - scholar.archive.org
Cilnidipine is a dual blocker of L-type voltage-gated calcium channels in vascular smooth
muscle and N-type calcium channels in sympathetic nerve terminals that supply blood …

[引用][C] I Cmt I

M JOIII - JSTOR

[PDF][PDF] Cilnidipine: next generation calcium channel blocker

MM Shete - J Assoc Physicians India, 2016 - researchgate.net
Hypertension is one of the most common conditions seen in primary care and a major public
health problem in India. It can lead to various complications if not detected early and treated …

[PDF][PDF] Cilnidipine: Preclinical profile and clinical evaluation

H Uneyama, H Uchida, T Konda… - Cardiovascular drug …, 1999 - academia.edu
Cilnidipine (FRC-8653) is a dihydropyridine (DHP) type of calcium channel antagonist
originally developed in Japan. Unlike other calcium channel antagonists, cilnidipine blocks …

Lercanidipine salts

A Leonardi, G Motta, M Von Raumer - US Patent 7,683,179, 2010 - Google Patents
The present invention provides novel acid addition salts of lercanidipine, including
amorphousand crystalline lercanid ipine salts and processes for making the same. The …

UV and RP-HPLC Method Development and Validation for Estimation of Cilnidipine

B Samantaray, S Kanhar, A Nanda - 2023 - scholar.sdpublishers.info
The current experiment was designed to develop and validate a simple RP-HPLC
methodology for determining Cilnidipine. Cilnidipine was quantified using UV spectroscopy …

[PDF][PDF] A review: analytical methods for determination of cilnidipine in biological fluid and pharmaceutical dosage forms

FV Buchiya, V Jain, H Raj - Pharma, 2014 - academia.edu
Cilnidipine is act as a dual blocker by blocking L-type of calcium channel present in vascular
smooth muscles and N-type of calcium channel present in sympathetic nerve terminal that …

Quantification of cilnidipine in human plasma by liquid chromatography-mass spectrometry

KR Lee, YJ Chae, JH Lee, DD Kim… - Journal of liquid …, 2012 - Taylor & Francis
A liquid chromatography-mass spectrometry (LC-MS) assay was developed and validated
for the quantification of cilnidipine, a calcium channel antagonist, in human plasma. Plasma …

[PDF][PDF] Development and Validation of Ultraviolet and Reverse Phase-high Performance Liquid Chromatographic Method for Estimation of Cilnidipine

B Samantaray, J Panda, S Mahapatra, K Ray, S Kanhar - 2021 - academia.edu
Aim: The current experiment was to develop and validate a straight forward RP-HPLC
methodology for the determination of Cilnidipine. Methodology: UV spectroscopy was used …

Lercanidipine hydrochloride polymorphs and an improved process for preparation of 1, 1, N-trimethyl-N-(3, 3-diphenylpropyl)-2-aminoethyl acetoacetate

G Dixit, KB Sharma, NS Pradhan… - US Patent App. 12 …, 2010 - Google Patents
Disclosed herein is an improved, commercially viable and industrially advantageous
process for the preparation of Sub stantially pure Lercanidipine intermediate, 1.1. N-trimethyl …