克雷白氏肺炎桿菌是一株伺機性的革蘭氏陰性病原菌, 可造成肺炎, 原發性肝膿瘍,
尿道和化膿性感染, 及敗血症等廣泛疾病. 我們實驗室先前利用小鼠活體表現技術(in vivo …

Klebsiella pneumoniae is an opportunistic Gram-negative pathogen that causes a wide
range of infections, including pneumonia, urinary tract, purulent infections, primary liver …

環狀雙鳥苷酸是許多細菌的二級傳訊分子, 負責調控纖維素的合成, 泳動能力,
生物膜生成以及毒力因子的表達; 此二級傳訊分子的濃度由雙鳥苷酸環化酶(diguanylate …

This study shows that the expression of yjcC, an in vivo expression (IVE) gene, and the
stress response regulatory genes soxR, soxS, and rpoS are paraquat inducible in Klebsiella …

Abstract C-di-GMP [Bis-(3′-5′)-cyclic-dimeric-guanosine monophosphate], a second
messenger is involved in intracellular communication in the bacterial species. As a result …

The bacterial second messenger bis-(3′-5′)-cyclic dimeric GMP (c-di-GMP) has been
shown to influence the expression of virulence factors in certain pathogenic bacteria, but …

Cyclic nucleotides represent second messenger molecules in all kingdoms of life. In
bacteria, mass sequencing of genomes detected the highly abundant protein domains …

Abstract Bis-(3'–5')-cyclic-dimeric guanosine monophosphate (c-di-GMP) is a bacterial
second messenger known to mediate the regulation of multiple cellular processes, including …

Second messengers play an integral role in regulating a wide variety of pathways in
response to triggers from the extracellular milieu. The intracellular second messenger cyclic …

Cyclic di-GMP (c-di-GMP) is a second messenger that regulates diverse cellular processes
in bacteria, including motility, biofilm formation, cell-cell signaling, and host colonization …