After an ischemic stroke (IS) occurs, immune cells begin traveling to the brain and immune
system from the gut and gastrointestinal tract, where most of them typically reside. Because …

Local ischemia often causes a series of inflammatory reactions when both brain immune
cells and the peripheral immune response are activated. In the human body, the gut and …

Stroke leads to inflammatory and immune response in the brain and immune organs. The
gut or gastrointestinal tract is a major immune organ equipped with the largest pool of …

Ischemic stroke is a highly complex systemic disease characterized by intricate interactions
between the brain and gastrointestinal tract. While our current understanding of these …

The microbiota–gut–brain axis is considered a central regulator of the immune system after
acute ischemic stroke (AIS), with a potential role in determining outcome. Several pathways …

As a vital pivot for the human circulatory system, the brain-gut axis is now being considered
as an important channel for many of the small immune molecules' transductions, including …

Stroke is primarily a neurodegenerative disease but can also severely impact the functions
of other vital organs and deteriorate disease outcomes. A malfunction of the gastrointestinal …

The gut contains the largest reservoir of microorganisms of the human body, termed as the
gut microbiota which emerges as a key pathophysiological factor in health and disease. The …

Gastrointestinal (GI) complications are seen in over 50% of ischemic stroke survivors; the
most common complications are dysphagia, constipation, and GI bleeding. The bidirectional …

The high incidence, mortality, and disability associated with ischemic stroke pose a
significant threat to human health. The intestinal microbiota significantly influences the …