大麻素和内源性大麻素作为治疗神经系统疾病的药物: 临床前模型和临床研究

RS Duncan, SM Riordan, MC Gernon… - 中国神经再生研究(英文 …, 2024 - sjzsyj.com.cn
Cannabinoids are lipophilic substances derived from Cannabis sativa that can exert a
variety of effects in the human body. They have been studied in cellular and animal models …

[HTML][HTML] Cannabinoids and endocannabinoids as therapeutics for nervous system disorders: preclinical models and clinical studies

RS Duncan, SM Riordan, MC Gernon… - Neural Regeneration …, 2024 - journals.lww.com
Cannabinoids are lipophilic substances derived from Cannabis sativa that can exert a
variety of effects in the human body. They have been studied in cellular and animal models …

Cannabinoid-based medicines for neurological disorders—clinical evidence

S Wright - Molecular neurobiology, 2007 - Springer
Whereas the cannabis plant has a long history of medicinal use, it is only in recent years that
a sufficient understanding of the pharmacology of the main plant constituents has allowed …

Cannabis: old medicine with new promise for neurological disorders.

GT Carter, P Weydt - Current Opinion in Investigational Drugs …, 2002 - europepmc.org
Marijuana is a complex substance containing over 60 different forms of cannabinoids, the
active ingredients. Cannabinoids are now known to have the capacity for neuromodulation …

Cannabinoids and neurodegenerative diseases

J Romero, J Martinez-Orgado - CNS & Neurological Disorders …, 2009 - ingentaconnect.com
Although significant advances have taken place in recent years on our understanding of the
molecular mechanisms of different neurodegenerative diseases, its translation into effective …

[HTML][HTML] Cannabinoids in the treatment of neurological disorders

O Devinsky, BJ Whalley, V Di Marzo - Neurotherapeutics, 2015 - Springer
The force of the recent explosion of largely unproven and unregulated cannabis-based
preparations on medical therapeutics may have its greatest impact in the field of neurology …

Emerging roles of cannabinoids and synthetic cannabinoids in clinical experimental models

P Morales, PH Reggio - Cannabinoids and Neuropsychiatric Disorders, 2021 - Springer
In recent years, an increasing number of investigations has demonstrated the therapeutic
potential of molecules targeting the endocannabinoid system. Cannabinoids of …

Therapeutic action of cannabinoids in a murine model of multiple sclerosis

Á Arévalo-Martı́n, JM Vela… - Journal of …, 2003 - Soc Neuroscience
Theiler's virus infection of the CNS induces an immune-mediated demyelinating disease in
susceptible mouse strains and serves as a relevant infection model for human multiple …

[HTML][HTML] Cannabinoids: new promising agents in the treatment of neurological diseases

S Giacoppo, G Mandolino, M Galuppo, P Bramanti… - Molecules, 2014 - mdpi.com
Nowadays, Cannabis sativa is considered the most extensively used narcotic. Nevertheless,
this fame obscures its traditional employ in native medicine of South Africa, South America …

[HTML][HTML] Cannabinoids as potential treatment for neurological diseases

M Gómez-Cañas, P Morales, V Satta… - Frontiers in …, 2022 - frontiersin.org
Due to the wide distribution of the endocannabinoid system (ECS) throughout the organism
and its role on the maintenance of the homeostatic balance in the body, the modulation of …