摘要多能干细胞(pluripotent stem cell, PSC), 包括胚胎干细胞(embryonic stem cell, ESC)
和诱导多能性干细胞(induced pluripotent stem cell, iPSC), 具有无限自我更新及分化成体内 …

Pluripotent stem cells (PSCs) are capable of generating all types of cells in the body and
have promising applications in basic research and cell-based regenerative medicine …

Pluripotent stem cells (PSCs) are able to generate all cell types in the body and have wide
applications in basic research and cell-based regenerative medicine. Maintaining stable …

血液疾病目前正威胁着世界数百万人的生命健康. 多数情况下, 移植健康或基因修复的,
具有长期移植能力的造血干细胞 (HSC) 是唯一的治愈方法. 然而, 人体 HSC 数量有限 …

2006 年, 日本科学家ShinyaYamanaka 通过转入4 个“干性基因” 将小鼠体细胞进行重编程,
诱导成为多潜能干细胞(inducedpluripotentstemcells, iPScells), 这一里程碑式的工作对再生 …

Reprogrammed pluripotent stem cells (PSCs) are valuable for research and potentially for
cell replacement therapy. However, only a fraction of reprogrammed PSCs are …

Stem cells hold enormous promise for regenerative medicine as well as for engineering of
model systems to study diseases and develop new drugs. The discovery of protocols that …

Pluripotent stem cells (PSCs) must maintain their proper genomic content in order to
preserve appropriate self-renewal and differentiation capacities. However, their prolonged in …

Pluripotent stem cells (PSCs) hold great promise in cell-based therapy because of their
pluripotent property and the ability to proliferate indefinitely. Embryonic stem cells (ESCs) …

Human pluripotent stem cells (PSCs), which include both embryonic and induced pluripotent
stem cells, are widely used in fundamental and applied biomedical research. They have …